Will any of the antibiotics become toxic over time?

Amoxicillin-Clavulanate- A penicillin antibiotic used in adults and children to treat bacterial infections such as bronchitis, urinary tract infections, pneumonia, and infections of the skin, throat, ears, lungs, and sinuses. Amoxicillin-Clavulanate is not toxic but may be less effective in treating infection beyond it’s expiration date.

Azithromycin- A macrolide antibiotic used in adults and children to treat bronchitis, pneumonia, Lyme disease, some sexually transmitted infections, and infections of the skin, throat, ears, lungs, sinuses, and reproductive organs. Azithromycin is not toxic but may be less effective in treating infection beyond it’s expiration date.

Ciprofloxacin- A fluoroquinolone antibiotic used in adults and children from the age of one when other antibiotics have not worked and used to treat severe skin and bone infections, chest infections, sexually transmitted infections, conjunctivitis, and ear infections. Ciprofloxacin is not toxic but may be less effective in treating infection beyond it’s expiration date.

Doxycycline- A tetracycline antibiotic used in adults and children over 12 years old and used to treat skin infections, sexually transmitted infections, chest and dental infections, and other rare infections. Doxycycline is not toxic but may be less effective in treating infection beyond it’s expiration date.

Metronidazole- A nitroimidazole antibiotic used in adults and children to treat skin infections, gum disease, dental abscesses, bacterial vaginosis, pelvic inflammatory disease, and various skin infections. Metronidazole is not toxic but may less effective in treating infection beyond it’s expiration date.