Will any of the antibiotics become toxic over time? - JASE Medical
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Will any of the antibiotics become toxic over time?

Antibiotic expiration dates indicate the final day that a particular manufacturer can guarantee the potency and safety of a specific medication. While studies of antibiotic stability are tested on products at two to three years, manufacturers consider long-term stability testing unnecessary because current expiration dates are considered an acceptable time frame. Research has shown that the potency of antibiotics extends beyond their published expiration dates, but these findings are not guaranteed.

Amoxicillin-Clavulanate- A penicillin antibiotic used in adults and children to treat bacterial infections such as bronchitis, urinary tract infections, pneumonia, and infections of the skin, throat, ears, lungs, and sinuses. Long-term usage appears safe, but the risk of severe side effects may increase significantly in elderly patients. If taken far beyond the expiration date, Amoxicillin-Clavulanate is not toxic but may be less effective in treating infection.

Azithromycin- A macrolide antibiotic used in adults and children to treat bronchitis, pneumonia, Lyme disease, some sexually transmitted infections, and infections of the skin, throat, ears, lungs, sinuses, and reproductive organs. If taken far beyond the expiration date, Azithromycin is not toxic but may be less effective in treating infection.

Ciprofloxacin- A fluoroquinolone antibiotic used in adults and children from the age of one when other antibiotics have not worked and used to treat severe skin and bone infections, chest infections, sexually transmitted infections, conjunctivitis, and ear infections. If taken far beyond the expiration date, Ciprofloxacin is not toxic but may be less effective in treating infection.

Doxycycline- A tetracycline antibiotic used in adults and children over 12 years old and used to treat skin infections, sexually transmitted infections, chest and dental infections, and other rare infections. If taken far beyond the expiration date, Doxycycline is not toxic but may be less effective in treating infection.

Metronidazole- A nitroimidazole antibiotic used in adults and children to treat skin infections, gum disease, dental abscesses, bacterial vaginosis, pelvic inflammatory disease, and various skin infections. If taken far beyond the expiration date, Metronidazole is not toxic but may less effective in treating infection.

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