Medication Spotlight: Dexamethasone

2.5 Million adults in the U.S. take corticosteroids (such as Dexamethasone)

Antibiotic Intervention Secondary Image

What is Dexamethasone?

Dexamethasone is a corticosteroid medication widely used for its anti-inflammatory and immunosuppressant properties. It helps reduce inflammation and modify the body’s immune response, making it effective in treating a variety of conditions in both adults and children.

It’s wide array of applications make it a valuable medication to have on hand in your emergency kit at home, should the need arise.

 

USES:

  • Inflammation
  • Acute altitude sickness
  • High-altitude cerebral edema
  • Certain eye conditions (uveitis, conjunctivitis, keratitis)
  • Severe allergies (by suppressing the immune system’s response to allergens)
  • Rheumatoid arthritis
  • Asthma

| 1.5 million people in the United States suffer from rheumatoid arthritis (RA), according to Yale Medicine

 

Antibiotic Intervention Secondary Image

 

Also, this medication is used in children to treat asthma, allergic reactions, some auto-immune disorders, croup, and pneumonia.

 

Dexamethasone is available as an add-on (only $27) to any Jase Case order, AND is also now included in every KidCase at no extra cost, just to make the KidCase more robust for our little ones.

 

Things to consider:

  1. Dexamethasone was on the list of drug shortages from 2019 into 2023
  2. In its injectable form is is still in short supply as of June 2024

Safeguard against potential shortages by having your own personal supply on hand in your Jase Case.

Lifesaving Medications

Everyone should be empowered to care for themselves and their loved ones during the unexpected.

Recent Posts

Keeping you informed and safe.

Medication Spotlight: Dexamethasone

Medication Spotlight: Dexamethasone

2.5 Million adults in the U.S. take corticosteroids (such as Dexamethasone)What is Dexamethasone? Dexamethasone is a corticosteroid medication widely used for its anti-inflammatory and immunosuppressant properties. It helps reduce inflammation and modify the body’s...

read more
Men’s Health Awareness Month

Men’s Health Awareness Month

Don't overlook regular checkups or mental health!June is Men's Health Month, a time to shed light on the importance of prioritizing well-being, and implement habits for a healthier lifestyle. We all know the basics of how to live a healthier life: eat healthy natural...

read more
Allergy Season and the Risk of Respiratory Infections

Allergy Season and the Risk of Respiratory Infections

Don't let allergies turn into something more serious!It’s that time of year. The weather is lovely, the flowers are in bloom, the birds are chirping, and the tissues are flying? Summer’s around the corner, and Spring is certainly in the air, but so are the allergens....

read more

Join Our Newsletter

Our mission is to help you be more medically prepared. Join our newsletter and follow us on social media for health and safety tips each week!

Silent Pandemic – Antibiotic Resistance

A dire warning from health leaders across the world are calling the silent pandemic- antimicrobial resistant (AMR) infections. According to the World Health Organization AMR is one of the top ten leading global threats to health facing humanity in the world.

CDC estimates about 47 million antibiotic courses are prescribed for infections that don’t need antibiotics, like colds and the flu, each year. That adds up to approximately 28% of all antibiotics prescribed. In addition, A study published in the Lancet found that antimicrobial resistance was the direct cause of 1.27 million deaths worldwide.

An ever-increasing number of bacteria, fungi and parasites are becoming resistant to commonly prescribed antibiotics, with some resistant to many different antibiotics.  In some cases, antibiotics are not effective, leading to impossible to treat infections. This is a chilling scenario we are facing.

Antibiotic resistance (AMR) occurs through either genetic mutation or by acquiring resistance genes- where the antibiotic resistance genes are transferred to the next generation.

Some of the most widespread and common examples include:

  • methicillin-resistant Staphylococcus aureus (MRSA) (The most common)
  • vancomycin-resistant Enterococcus (VRE)
  • multi-drug-resistant Mycobacterium tuberculosis (MDR-TB)
  • carbapenem-resistant Enterobacteriaceae (CRE) gut bacteria

Broad spectrum antibiotics- The good and the bad

Broad spectrum antibiotics are being used in more and more AMR cases. These are antibiotics that act on the two major bacterial groups, gram-positive and gram-negative or any antibiotic that acts against a wide range of disease-causing bacteria. They are lifesaving when no other antibiotic therapy is working.

 They do come, however with their own set of whole set of detrimental, long lasting health effects. Some of these include resistance to pathogens, altered gut microbiota and immune system dysfunction. This is especially detrimental in young children. Broad spectrum antibiotics can alter gut microbiota which in turn will disrupt and affect immune function and growth of the child.

Promising research to fight antibiotic resistance

A protein in antibiotic resistant bacteria called DsbA helps fold resistance proteins into the right shapes to neutralize antibiotics. This was discovered by researchers, including experts from Imperial College London, led by Dr Despoina Mavridou assistant professor in Molecular Biosciences at the University of Texas at Austin. By disrupting the DBsA protein the team was successful in neutralizing the antibiotic resistant protein. In addition the pathogen was more sensitive to common antibiotics. As of this writing, research has been limited to outside the human body. The team now plans on finding an inhibitor that can be safely used in humans providing the same effect.

How to prevent AMR

Until research can successfully develop therapies for AMR, staying healthy and using antibiotics only when necessary are our options. Also, avoid crowds during outbreaks. And if sick, stay home!

The most effective way to prevent AMR is to boost immune system through:

  • Quality sleep- Sleep is when the body actively heals and restores health. Practice sleep hygiene
  • Exercise- At least 30 minutes several times a week of active walking or other form of exercise can help boost immune system, regulate mood and decrease appetite
  • Avoid sugar-Sugar and refined carbohydrates help feed pathogenic bacteria
  • Vitamin D (with k2)- Vitamin D supports a strong immune system. Talk with your healthcare provider about vitamin D supplementation and checking vitamin D levels to make sure you are reaching optimum vitamin D levels
  • Avoid and manage stress- Deep breathing exercises can help when unable to avoid stressful situations.
  • Practice personal hygiene- wash hands after going to store, before eating, and any time your are exposed to anyone who is ill.

- Brooke Lounsbury, RN

Medical Content Writer

Lifesaving Medications

Everyone should be empowered to care for themselves and their loved ones during the unexpected.

Recent Posts

Keeping you informed and safe.

Join Our Newsletter

Our mission is to help you be more medically prepared. Join our newsletter and follow us on social media for health and safety tips each week!

Prepared Equals Peace of Mind

Prepared equals peace of mind

What is labeled “prepping” or being a “prepper” used to be how everyone lived as recent as 50 years
ago. Our just- in- time supply chains weren’t around back then. Amazon, and online shopping didn’t
exist. Back then, if you wanted something you had to either call the company and place an order or mail
a check in.

The Sears catalog, along with many other catalogs would arrive and you and your family would spend
hours poring over the pages. These pages were filled with almost anything you may need or want, from
bed sheets to tools for the shop. In essence, those catalogs were the modern-day equivalent of Amazon.
Sometimes it would take a month or so for the much-awaited order to arrive. This was normal. Back
then, if you wanted something you had to plan for it.

Just in time supply chain

Fast forward to today. With all the wonderful technology, the same day deliveries, and almost any item
at our disposal within a few days, we have become complacent. Don’t get me wrong, we have used this
system to receive much needed items, in some cases almost immediately. This is the wonder of our
technological age. But it comes at a price. We take for granted that these supply chains will always be
running smoothly. Our world economy, for the past several decades has made life more convenient and
opened our lives to new experiences and time saving devices.
Technology- double edged sword

Our global world is a double-edged sword. The convenience we so much rely on, can and has been in the
process of failing over the past few years. The consequences to our healthcare system have been
devastating. Medical supplies such as contrast dye and drugs, have been in short supply or altogether
unavailable with no end in sight. This illustrates how fragile our medical system is. We are only one
natural or manmade disaster, pandemic, political or civil unrest from the complete shutdown of life
saving drugs and medical supplies.

Pharmaceuticals outsourced

The last major pharmaceutical manufacturing operation closed its doors and left the United States in
2004. Since then, nearly all the active ingredients for antibiotics and chronic medications – even
vitamins – are produced overseas, mainly in China and India.
Take, for instance the current amoxicillin shortage.

Across the country many pharmacies have reported a limited or not available supply of amoxicillin.
Amoxicillin is one of the first antibiotics used to treat strep throat, ear infections, urinary tract infections
and many other infections. The shortage includes amoxicillin in pill form, powder to mix with water to
make a suspension, and chewable tablets.

The American Society of Healthcare Pharmacists maintains a database of drug shortages and
manufacturers. They have listed amoxicillin manufacturers who have reported shortages or no
availability.

• Aurobindo, with facilities located throughout the world, refuses to provide availability
information.
• Hikma, based out of the UK, did not provide a reason for the shortage.
• Rising, based out of New Jersey has amoxicillin capsules and tablets available, but doesn’t state
whether they have amoxicillin powder available
• Sandoz, headquartered in Switzerland did not provide a reason for the shortage.
• Teva, which is based out of Israel did not provide a reason for the shortage.

However, the FDA states the only shortage is amoxicillin in powder form. This is because if even one
manufacturer can supply the necessary drug there is no perceived shortage.

This is very disturbing. All it takes is that one manufacturer to declare either a shortage or the drug
not available at all and the US supply is dried up.

Augmentin, (amoxicillin / clavulanate) is one of the antibiotics included in the Jase Case (see below how
to order a Jase Case). This can be substituted for amoxicillin if amoxicillin isn’t available.

Generics less likely to be manufactured

An analysis conducted by the US Pharmacopeia, a group that sets standards around the world for
medicines, found that antibiotics are 42% more likely to be in shortage in the US compared to other
types of drugs. Most antibiotics are now generic.

According to an analysis by the FDA Report “Drug Shortages: Root Causes and Potential Solutions”
identified three root causes of drug shortages.

1. Lack of incentives for manufacturers to produce less profitable drugs. (Generics aren’t very
profitable)
2. The market does not recognize and reward manufacturers for “mature quality systems” that
focus on continuous improvement and early detection of supply chain issues; and
3. Logistical and regulatory challenges make it difficult for the market to recover from a disruption.
The fragile global supply chains mean that if a pharmaceutical factory is down in China, you may not be
able to find your prescription at the neighborhood pharmacy. Lifesaving antibiotics are at risk of running
out faster than any other medicine. Medicines that are now available could easily run out. This could
lead to dire consequences.

Jase Medical is on a mission

JASE Medical is a telemedicine company with a singular focus to change all of that. This platform offers
access to basic emergency preparedness medications for every family in America.

And how will they do that? Well, it won’t happen overnight. But JASE Medical has done its homework
and established a nationwide network of physicians trained to evaluate individual needs, assess
conditions, and prescribe appropriate prescriptions for emergency preparedness purposes. From there,
licensed pharmacists fill your prescription, and the Jase Case is sent to your home.

These are the medications that will become lifesaving for you and the people you care about. And it’s all
done online through the JASE Medical portal.

How it works

When you log on to the platform and begin your consultation, you will find a simple and user-friendly
experience. The consultation takes little over five minutes to complete. After a licensed Jase healthcare
provider has reviewed your health history and any allergic reactions to medications, your prescriptions
are filled, and your Jase Case is shipped to your front door.

What’s in the JASE Case?
The kit contains the following antibiotic medications:
 Amoxicillin/Clavulanate.
 Azithromycin.
 Ciprofloxacin.
 Doxycycline.
 Metronidazole.
(Substitutions are made if allergic to one of the antibiotics)

All medications carry a level of risk, but these five antibiotics were selected for their effectiveness and
optimal patient safety. Guidance from the CDC says it best: “Antibiotics … save lives, and when a patient
needs antibiotics, the benefits usually outweigh the risks of side effects and antibiotic resistance.”

Some of the infections a Jase Case can treat
 Anthrax, plague and tularemia (resulting from bioterror).
 Bite wounds.
 Cellulitis.
 Diverticulitis.
 Intra-abdominal infections.
 Tooth infections.
 Ear infections.
 Pneumonia.
 Sinusitis.
 Strep throat.
 Urinary tract infection.
 and more.

When access to your healthcare provider isn’t possible (you are on vacation, etc.) your Jase case
includes a symptom and antibiotic use handbook titled the “Emergency Antibiotic Guide “with easy-to-
follow instructions to ensure proper use of the antibiotics if indicated.
What about chronic conditions?

Soon, the JASE Medical platform will provide emergency preparedness medicines for those with chronic
medical conditions (such as blood pressure and other chronic conditions). JASE Medical’s same
physician network will assess your condition and the need for appropriate preparedness medicines.

Ongoing support

As part of its mission to prepare you medically, JASE Medical provides unlimited ongoing support from
their physician network for questions about any of the medications prescribed.

What about shelf life?

The good news about antibiotics is that they last longer than you think. The FDA’s Shelf-Life Extension
Program found that 88% of the drugs studied maintained their potency and safety beyond the published
expiration date. The extended usability of these medications ranged from 5.5 years to as many as 23
years beyond their printed expiration!

The JASE Case antibiotics all carry the FDA’s required expiration dates. JASE Medical endorses those
dates.

Value and peace of mind

At the end of the day, this is all about peace of mind and knowing that you are ready for the
unexpected. Knowing that you have found a solution, priced at a fraction of what it would otherwise
cost you, adds to that peace of mind.

Go to JaseMedical.com and secure your emergency medications, an emergency antibiotic guide,
unlimited physician consultation and a team of professionals who are on a mission to keep you and your
loved ones prepared and safe during these uncertain times.

- Brooke Lounsbury

Medical Content Writer

Lifesaving Medications

Everyone should be empowered to care for themselves and their loved ones during the unexpected.

Recent Posts

Keeping you informed and safe.

Join Our Newsletter

Our mission is to help you be more medically prepared. Join our newsletter and follow us on social media for health and safety tips each week!

Ivermectin back in stock! | Add it discounted to a Jase Case order today

X