Infection - JASE Medical

Avian Influenza (Bird Flu): It’s Resurgence, Risks, and Treatment

The Importance of Timely Antibiotic Intervention

They call it the bird flu, but it also affects other animals, and people.

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Making an Unwelcome Comeback

Back in the mid to late 2000’s the bird flu was on a devastating path around the world – killing 53% of humans who contracted it. States of emergency were declared, experimental vaccines developed, and antiviral drugs (such as Oseltamivir) were stockpiled. Since then it was pretty much relegated to wild bird populations, until recently. 

The bird flu has been around for decades and is a constant health risk to wild bird populations, but it normally stays there, amongst wild birds. In more recent years however, it has infiltrated other birds, including commercial poultry animals, and beyond. 

The Current Situation:

In recent months, the world has been grappling with a concerning resurgence of the avian influenza, commonly known as bird flu. This highly pathogenic influenza results in a viral infection, primarily affecting birds, but has raised alarms due to its potential to spread to other birds and mammals, including humans.

The H5N1 strain has been affecting wild birds in the United States since about 1996, but lately has also spread to poultry farms, leading to the culling of millions of birds to prevent further spread. But this has only been partially successful. 

In late March 2024, the virus was detected in dairy cattle in Texas and Kansas, marking the first time it was found in mammals in the U.S. this year.

And there have been two confirmed human cases in the U.S. so far this year. 

The current outbreak of bird flu has been primarily attributed to the H5N1 and the more recent H5N8 strains of the virus. These strains are highly pathogenic, meaning they can cause severe illness and death in birds. The virus is primarily spread through contact with infected birds or their droppings, though it can also be transmitted through contaminated surfaces or objects. It was exposure due to close proximity to infected animals that caused the two human cases. One case involved a worker at a farm with infected cows, and the other case involved a worker at a poultry facility.

 

Risks to Humans:

While H5N1 can infect humans through close contact with infected birds or mammals, the current risk to the general public is considered relatively low. The CDC’s avian influenza risk information changes, and gets updated regularly though.  However it is a non-zero risk. The two human cases in the U.S. this year involved direct contact with infected animals, but there is currently no evidence of sustained human-to-human transmission. 

When contracted, the H5N1 strain in particular, has been known to cause severe respiratory illness in humans, with a potential for prolonged health complications if not treated effectively.

Another strain of concern, H5N8, has also shown the ability to infect humans. While human cases of H5N8 have been limited so far, the potential for the virus to mutate and become more transmissible among humans is a significant concern. 

Genetic changes in the virus have enabled the bird flu to spread from wild birds to poultry animals and other mammals, including livestock and humans. And while it doesn’t pose an immediate risk to the general public, the time to prepare yourself for it is before it gets worse – not after.

 

What can we do?

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While we can’t avoid wild birds or poultry altogether, here are some steps we can take to reduce the risks of infection:

 

  1. Avoid Contact with Sick or Dead Birds: Do not handle sick or dead birds, including poultry. If you must handle them, use gloves and other protective gear, and wash your hands thoroughly afterward.
  2. Practice Good Hygiene: Wash your hands frequently with soap and water, especially after handling birds or visiting places where birds are present. Avoid touching your face, especially your eyes, nose, and mouth, with unwashed hands.
  3. Cook Poultry Thoroughly: Ensure that poultry, including eggs, is cooked thoroughly before consumption. Cooking at temperatures of 165°F (74°C) kills the bird flu virus.
  4. Avoid Contaminated Surfaces: Avoid contact with surfaces or objects that may be contaminated with bird droppings or secretions.
  5. Limit Exposure to Live Birds: Minimize visits to live bird markets or farms where poultry are raised, especially in areas experiencing bird flu outbreaks.
  6. Stay Informed: Stay updated on the latest developments regarding bird flu outbreaks in your area and follow the advice of health authorities.
  7. Be equipped to treat an infection if it occurs. Keep an antiviral medication on hand. 

 

Antivirals treat Avian Influenza

Antiviral medications, such as Oseltamivir, remain the preferred intervention method for most influenzas including the bird flu. Stopping a viral infection as soon as possible yields the best outcome for patients, and having a medication kit that includes an antiviral is key to being able to intervene quickly in an infection. Early treatment means you’ll feel better faster, and have less disruption to your daily life. It also means you’ll reduce the likelihood of developing further complications.

Our Jase Case  – already full of life saving medications – is also completely customizable, and can be configured to include the antiviral Oseltamivir 75 mg (10 pack) so you have a weapon to wield against the bird flu (and other influenzas).

Customize your Jase Case today, for some certainty in an uncertain world. 

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The Importance of Timely Antibiotic Intervention

The Importance of Timely Antibiotic Intervention

Accelerate healing through early treatment. .The Key to Effective Infection Management: Early antibiotic intervention and at the right dose. While aggressive antibiotic treatment with high dosages has been the go-to methodology of treatment historically, research by...

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Navigating Spring’s Waters: Hydration, Recreation, and the Risk of Giardia

The Importance of Timely Antibiotic Intervention

Even crystal clear water can conceal hidden hazards.

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Spring Brings water, water brings risks. 

With spring in full swing and temperatures rising, our thirst (pun intended) for water grows as well. This applies to both the need to stay hydrated and the desire to cool off in our pools, lakes and rivers. As we welcome this wave of water in our lives, it’s important to remember that exposure to hidden perils, such as water-borne illnesses like Giardia, also rises.

 

 

Giardia is the most common intestinal parasitic disease in the U.S. and affects about 1 million people a year.

 

Just how easy is it to get infected?

Giardia spreads very easily. While most commonly contracted through exposure to contaminated water, it can also be spread through contaminated food, surfaces, objects, and even exposure to a person infected with the parasite.

It’s not only potentially contaminated drinking water sources you have to worry about when camping or spending time in the outdoors, but also natural and man-made bodies of water you may use for swimming or water sports (lakes, ponds rivers, streams, public water supplies, wells, cisterns, swimming pools, water parks and spas).

Faucets can provide a false sense of security. Also of high concern is questionable tap water in certain areas you may travel to. Even if you don’t drink it, you may still likely use it for brushing your teeth or showering – which can potentially expose you to Giardia just the same.

What can you do? The best thing you can do to mitigate exposure is be cautious of the sources of the water you consume, and be aware of the potential animals in the surroundings of the water you swim and play in – as they likely use that water too.

Bring your own drinking water or only consume bottled water in places you travel to. If you must use tap water for drinking in a location you are unsure of, then boil the water, use a water filter, or purification tablets.

What if I get exposed to Giardia? Fortunately Giardia infection is not fatal, but can lead to complications in certain individuals if not treated. Reactive arthritis, irritable bowel syndrome, and recurring diarrhea that can last for years are among the worst prognoses one can be diagnosed with.

 

 

Exposure Rates are High, Effective Treatment is Available

Metronidazole for Treatment of Giardia Infections:

The good news is treatment for Giardiasis exists and is very effective. Metronidazole is the most common and potent medication for Giardia infection, but is not available over the counter. A 5-7 day course of Metronidazole tablets is usually enough to eliminate the infection and its symptoms in over 90% of patients.

Why you should have Metronidazole on hand:

In addition to treating parasitic Giardia infections, Metronidazole is also used to treat certain skin infections, rosacea, oral infections including infected gums or dental abscesses, and bacterial vaginosis and pelvic inflammatory infections.

While you can’t pick up Metronidazole at the store on your family weekend getaway, you can have it with you in our Jase Case, as one of the standard medications our kits come with.

Each standard Jase Case also comes with medications for other infections and illnesses including pneumonia, sinus infection, urinary tract infections, traveller’s diarrhea, Lyme disease, skin, infections and more.

And you can customize your Jase Case with over 30 available add on medications from EpiPens (anaphylaxis), to Ivermectin (parasitic infections), to treat just about anything you may encounter from Influenza (Oseltamivir) to Malaria (Atovaquone-Proguanil).

If there were a prescription for peace of mind, it would be a Jase Case.

Lifesaving Medications

Everyone should be empowered to care for themselves and their loved ones during the unexpected.

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The Importance of Timely Antibiotic Intervention

The Importance of Timely Antibiotic Intervention

Accelerate healing through early treatment. .The Key to Effective Infection Management: Early antibiotic intervention and at the right dose. While aggressive antibiotic treatment with high dosages has been the go-to methodology of treatment historically, research by...

read more

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The “Last of Us” Mirrors Reality

In an eerie turn of events the widely popular HBO series “The Last of Us” could be based on an actual case of a fungal infection of Chondrostereum purpureum that occurred in India. In the series a fungus, Ophiocordyceps unilateralis infects and transforms humans into terrifying zombies, known as the “infected”.

The yet to be released June 2023 report of Medical Mycology states that a 61 year old man, a mycologist who had been working with plant fungi and decaying material, had been experiencing recurrent hoarseness of voice, cough, fatigue and lack of appetite for the past 3 months. There was no date given as to when this event occurred.

A CT scan revealed a right paratracheal (on the side of the windpipe) abscess. The abscess was aspirated and sent for evaluation.

After a series of tests were performed it was identified as a fungus, however the researchers couldn’t identify what type and sent the specimen off to the “WHO collaborating Centre for Reference & Research on Fungi of Medical importance” in India. It was identified as Chondrostereum purpureum by DNA sequencing. (D+28).  He was put on a course of antibiotics for two months. After 2 years of follow up the patient showed no evidence of reoccurrence. It is believed he was infected by working closely with and repeatedly inhaling spores from the plants he was working with for an extended time.

Until this case, there had been no evidence humans could be infected by this fungus. Fungal infections have historically affected immunocompromised individuals- until now. The man was not immunocompromised- had no history of diabetes, any chronic disease, immunosuppressive drug intake, or trauma. This raises serious concerns and questions about who is at risk.

What is Chondrostereum purpureum?

Chondrostereum purpureum is a fungal pathogen that causes silver leaf infection in trees and shrubs. It mostly attacks members of the rose family but also attacks apples, pears, plums, maples and many other deciduous plants. The fungus infects the wood through wounds in the plant and causes a silvering of the leaves followed by death of the branch.

Chondrostereum purpureum used as a mycoherbicide in Canada- And the United States

Deemed “safe” for humans and animals

(What could possibly go wrong?)

January 4, 2002 ,Myco-Tech™ Paste and Chondrostereum purpureum(HQ1), manufactured by Myco-Forestis Corporation was approved by the Ottawa,Ontario Pest Management Regulatory agency. Applied as a paste, this fungus inhibits the sprouting and regrowth on cut stumps of deciduous tree species susceptible to the fungus and kills them. March 30, 2005, the EPA registered and approved Myco-Tech™ Paste. In 2007 the Myco-Forestis corporation dissolved and in 2008 registration lapsed. At the time, the paste had a very short shelf life of only 3 months.

In 2004 after much research into extending the shelf life, Chontrol Paste, developed by MycoLogic Inc. was approved for registration. The city of Toronto uses this paste for invasive buckthorn control.

In the United States Chontrol Paste has been used in southeast Oregon to control tanoak. This product is available for use throughout the United States.

Pathogenic fungi are an emerging threat

Chondrostereum purpureum is not the only fungi that has the infected humans. Candida aurus has been taking center stage ever since it was discovered that the cases has more than tripled since 2019. Candida aurus is mostly found in hospitals among immunocompromised individuals. It is spread by direct contact with infected individuals, on surfaces such as hospital beds and items and can live for several months. Some hospital disinfectants are ineffective in killing the fungus. It has a mortality rate of between 30 and 60%. It is often multi drug resistant and is fast becoming an emerging global threat, according to the Center for Disease Control (CDC).

Fungi are hard to detect in the conventional laboratory setting and often have to be sent to specialty labs for identification. In addition, they have the ability to mutate, just like bacteria, placing them as another antibiotic resistant global health threat.

- Brooke Lounsbury, RN

Medical Content Writer

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