For Clinicians | Appropriate Medical Preparation

For Clinicians | Appropriate Medical Preparation 

The Clinical Category We’ve Been Practicing Without a Name

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Medically reviewed by Kristen Carpenter, PA-C — Clinical Advisory Board Member

Patients have been asking us a version of the same question for years. “What’s reasonable to have on hand,…… just in case?” Most of us don’t have a clean answer.

  • The toddler spiking a fever past 11pm after the only instacare in town just closed. 
  • The UTI that announces itself Friday at 6pm with a weekend ahead.
  • Pink eye Sunday morning with school Monday. 
  • Strep in a rural county where the nearest ER is three hours away and urgent care closed at 6. 
  • The pharmacy that’s open but out of stock on the antibiotic the prescriber just called in
  • The cruise-ship UTI on night three. 
  • A traveler’s fever in a hotel in a country where nobody at the front desk speaks English. 
  • A national pharmacy chain offline for two days after a ransomware attack. 
  • A maintenance refill backordered the week of a long-planned trip. 

Different sizes of disruption, same shape underneath: a moment when primary care isn’t reachable, and the patient doesn’t have what they need on the shelf.

Our patients have been living in this middle for years without a word for it. We are giving it one: appropriate medical preparation. A clinically grounded buffer to primary care, not around it.  Common, predictable medical disruption that ends with an avoidable ER bill, a missed dose, a ruined vacation, or just a really bad week.


Between full healthcare and full prepper

Right now, patients are choosing between two answers. Full healthcare, available when you’re close to the doctor and the pharmacy and the schedule is cooperating. Or full prepper, where the assumption is help isn’t coming. Neither was built for the life they actually live. The institutional advice in between (FEMA’s 72-hour kit, the written medication list every family is told to clear) is what everyone’s told to have, but in practice almost no family does.¹

Patients are hungry for something better. Access. Travel. Geography. Timing that doesn’t fit a normal clinic schedule. The things that go wrong on a Friday night don’t wait for Monday morning. When healthcare doesn’t fill the gap, patients fill it themselves, often from dubious sources online, because they need a real answer and someone has to give them one.

The disruption doesn’t even need to be exotic to be miserable. My brother-in-law spent an hour and a half in a seemingly neverending line at 9pm on a Friday at the only 24-hour pharmacy in his county (and at 750K+ people, it’s not a small, rural podunk county). Just Friday at 9pm, not even a holiday weekend. The whole evening was gone for something he should’ve been able to have on his own shelf ahead of time.

Survival medicine has its place for the long-term disruptions where help really isn’t coming. But for the disruptions that fill most families’ calendars, the question isn’t whether help is coming. It’s whether the family already has what they need on the shelf, before the wait causes major inconvenience and perhaps deterioration in their condition. That’s what we’re building into: a clinical bridge that meets patients where they are, instead of asking them to work around healthcare hours that aren’t always in their best interest.


What’s actively short in summer 2026

In Q1 2026, ASHP counted 223 active national drug shortages, the second consecutive quarter the count has risen⁵. The mix isn’t the headlines you might remember.

ADHD stimulants: amphetamine mixed salts (IR and XR), lisdexamfetamine, and methylphenidate ER are in their fourth year of active shortage. Specific strengths of amphetamine XR had release dates as recently as mid-May and early-June 2026.

Sterile injectable chemotherapy: vinblastine, methotrexate, and cisplatin are all currently short. Vinblastine is the most-shorted oncology drug, reported in shortage at 57% of surveyed centers⁶.

Injectable opioids: morphine sulfate (on the FDA shortage list since 2017) and fentanyl citrate (since 2012) remain chronically short. Acute pain, surgical anesthesia, palliative care.

Estradiol and progesterone: added to the shortage list in January and February 2026. Demand is up; manufacturing capacity hasn’t caught up.


The guidelines that haven’t been written

Naming the category is half the work. The other half is writing the clinical guidelines that define it: what patients can safely have on hand before a clinical event arrives, and how to use it well when it does. Clinicians love guidelines and frameworks, and the ones for this category have not been written yet. We are building them.

Appropriate medical preparation is, in no way, a replacement for primary care. Chronic conditions and the long-term continuity that primary care exists to provide belong in the exam room. We are here for the moments primary care isn’t, not for the moments primary care is. The line is sharp and we hold it.

What it actually is: a clinically grounded model of preparation, built by a team of board-certified physicians, physician assistants, and pharmacists. Protocols are reviewed. Decisions are cross-checked. Medications are matched to common and predictable conditions where the clinical decision is well-understood. When something changes after the patient has the medication on the shelf, the team is reachable by call or email, no runaround. The work is structured around preparation, before symptoms arrive.

And it is not fear-based stockpiling dressed up in clinical language. The doomsday posture sold as health care is a different category. Ours stays in the lane of common, predictable conditions where the clinical evidence is settled.


The work the literature already supports

Any clinician in practice more than a few months has seen this conversation in a dozen different costumes. The patient calling Friday at 4:55pm…….the colleague who watched a UTI hijack a family’s vacation……the pharmacist taking the 9pm phone call asking about an antibiotic shortage with no known arrival date for the backordered amoxicillin² and the parents are really upset because the other pharmacy that can get it in is closed for the weekend……the provider who got the late-night text from a friend traveling abroad asking how he can get an antibiotic for strep overseas. We have been navigating this informally for years, one patient at a time, with no shared language and no defined framework.

The reason is partly that we were trained for a different system. Pharmacy school, medical school, PA school all assumed a closed loop: one patient, one prescriber, one chart, one local pharmacy that knew about all three. That loop is gone. Patients now have access to direct-to-consumer telehealth, mail-order chains, foreign pharmacies, cross-border purchasing, online communities, and TikTok dosing advice³. The job is harder than the one we trained for: guiding patients toward appropriate access in a landscape where access is everywhere and quality is uneven.

The frame for this kind of work already exists in the literature. The Patient Activation Measure has documented for two decades that clinical outcomes improve when patients are activated and prepared to participate in their own care. Appropriate medical preparation is clinician-supported patient activation, not patient autonomy alone. The category needs both halves; neither one works on its own.


Charting the gray area in public

Public knowledge gets better when clinicians chart the gray area in public, instead of leaving the internet to do it. Patients today can get almost anything they want from an online pharmacy. Without a clinical voice in that conversation, they will keep filling the gap themselves, more often and with less guidance. We’re choosing to do that work in the open.

What we are doing right now is defining what is safe to have on hand and what is not, and edging out the boundaries of the category as we go. We are confident doing this work. We are also finding it is more complex than it sounds. A UTI workup is straightforward. Building a complete framework for the range of conditions a reasonable family could face is a different scale of clinical work. Not impossible. Just hard to do well in the cracks of an office visit. If you are doing this work for your own patients, we champion that. If you would rather refer or follow along, both options are here. You can refer at Jase.com, or follow our work as we share how we are thinking about it.

What we are sharing going forward: how we make clinical decisions, where we draw the lines, what the evidence supports, what we’re still working through. The category is new. The protocols are being written at the highest clinical standard we know. We want medical professionals at the table while we build, not after.


Building this in the open

This article is one of many we are writing. The category needs a clinical framework, written and revised in public, and we are starting that work here. Each week we will be sharing a piece of it: a condition we are working through, a protocol, a decision we made and why, a question we are still chewing on, and current news stories and how they relate to appropriate medical preparation.

If this is interesting to you….follow along! We are publishing a few times a week, having a lot of fun building this in the open, and we would love to have you join us. 


Sources

  1. FEMA. 2023 National Household Survey on Disaster Preparedness: Key Findings. Federal Emergency Management Agency, Individual and Community Preparedness Division, 2023. https://community.fema.gov/PreparednessConnect/s/article/Results-from-the-2023-National-Household-Survey-on-Disaster-Preparedness
  2. Brewster RCL, Khazanchi R, Butler A, O’Meara D, Bagchi D, Michelson KA. The 2022-2023 Amoxicillin Shortage and Acute Otitis Media Treatment. Pediatrics. 2023;152(3):e2023062482. https://pmc.ncbi.nlm.nih.gov/articles/PMC10895544/
  3. Trilliant Health. Telehealth Demand: An Update Four Years After the Onset of the COVID-19 Pandemic. Trilliant Health Market Research, 2024. https://www.trillianthealth.com/market-research/studies/telehealth-demand-an-update-four-years-after-the-onset-of-the-covid-19-pandemic
  4. Hibbard JH, Stockard J, Mahoney ER, Tusler M. Development of the Patient Activation Measure (PAM): Conceptualizing and Measuring Activation in Patients and Consumers. Health Services Research. 2004;39(4 Pt 1):1005-1026. https://onlinelibrary.wiley.com/doi/10.1111/j.1475-6773.2004.00269.x

 

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For Clinicians | Off-Grid Health Care: A Guide to Medical Preparation When the System Fails (aka SHTF)

For Clinicians | Off-Grid Health Care

A Guide to Medical Preparation When the System Fails (aka SHTF)

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Edited and approved by Kristen Carpenter, PA-C — Clinical Advisory Board Member

Your patient has already Googled “SHTF medical” at 11pm. They didn’t bring it up at the visit because they don’t think you’ll know what to say. They might be right.

They are not alone. Behind every shortage story (saline, Adderall, Ozempic, amoxicillin liquid, the two weeks of hurricane evacuations that emptied a region’s pharmacies), patients are running a quiet clinical question through their head: “What’s reasonable to have on hand,…… just in case?”
Most of us were never trained to answer it. Yet, when we hedge, the prepper internet doesn’t. It tells them to buy fish antibiotics and trust no one. Our silence on the subject isn’t helping our patients: it’s giving them only extremes to turn to for answers.

Today we’re talking about this question. The category is appropriate medical preparation, sized to the disruptions families actually face, not a doomsday-world-is-ending scenario.

The framework breaks into five modules: medication, trauma and wound care, water and sanitation, power and continuity, and household-specific layers. A sixth, capability, makes the rest work or not.


Medication: chronic supply, contingency supply

This is where preparation actually starts, and where the bulk of the work is. The hurricane Katrina chronic-disease data is dated but still the cleanest evidence we have on what happens when a region’s pharmacies go offline, settles the question of priority. Of medications dispensed to evacuees in San Antonio, 68% were for chronic disease. Cardiovascular alone was 39%. The federal stockpile supplied 9%. Retail pharmacies covered 73%¹.

What we don’t really recognize here is that the patient’s own medicine cabinet is the primary line. Federal caches and DMAT formularies are backstops, not plans.

So the first tier is the chronic supply, patient-owned. A 90+ day on-hand supply of every prescription the household can’t go without, paired with a written list any pharmacist can act on (drug, dose, prescriber, pharmacy). You might object that this isn’t preparation, it’s just well-managed primary care. Yep. That’s the point. The category isn’t separate from primary care. It’s primary care that takes evacuation, supply chain disruption, and Friday-night closures seriously. Ready.gov anchors a 3-day baseline kit². Disaster medicine literature pushes 30 to 90 days for chronic meds³. What actually holds up in a big disaster is closer to 90 days to have on hand.

The trickier prescriptions to navigate are controlled substances. Schedules III through V are workable. During a governor’s declaration, pharmacists in most states can dispense an emergency supply (typically up to 30 days) without a new prescription on file⁵. Coverage varies by state but typically includes medications like benzodiazepines, tramadol, and codeine combinations, the prescriptions most likely to surface in a sheltered population.

Schedule II is the cliff. Stimulants and most opioids. A declared disaster does not, by itself, authorize a Schedule II refill. That takes a fancy, specific DEA waiver, and the waivers are inconsistent. We don’t endorse stockpiling. We also don’t have a clean way to tell a patient on a Schedule II to save some each month, because clinically that’s the opposite of how these medications are supposed to be taken. There is a gap. They should just know ahead of time, and so should we, that navigating this one is inherently just going to be very tricky.

The second tier is the contingency supply. The prescription half: short-course antibiotics, antifungals, rescue inhalers, oral rehydration salts, basic wound care. The OTC half: acetaminophen, ibuprofen, diphenhydramine, loperamide, antacids, electrolyte tablets, meclizine, loratadine, bismuth subsalicylate. The clinical logic for the prescription half is the same one telehealth platforms already use for the same conditions, with the same prescribing patterns and the same evidence base. The only difference is timing. Same medications, same standards, prescribed before symptoms arrive instead of after.

This is the gap JaseCase is built to close: amoxicillin-clavulanate, azithromycin, ciprofloxacin, doxycycline, metronidazole, a methylprednisolone dosepak, ondansetron, triamcinolone topical, plus the OTC backbone.


Trauma: bleeding control, wound care, burns

The medication layer is what you have when the pharmacy is gone. The trauma layer is about what you do in the minutes before EMS can get there. Hemorrhage is the only category of injury where a layperson can credibly outperform “wait for the ambulance,” and that’s the core of this section.

Stop the Bleed has been around long enough that most clinicians know the program by name, but the kit itself doesn’t follow most patients home. The core list is short and CoTCCC-vetted: a CoTCCC-listed windlass tourniquet, hemostatic-impregnated gauze (kaolin-based is the canonical mechanism), a 4 to 6 inch pressure dressing, nitrile gloves, trauma shears, and a permanent marker for time-of-application⁶. Skill-retention data argue for refreshing training every 1 to 2 years⁷. The fact that a tourniquet is in the kit doesn’t mean a patient knows when to reach for one.

That set, plus a pair of vented chest seals, a space blanket for hypothermia prevention, and a casualty card, is what separates a real household IFAK from a box of band-aids. NPAs and needle decompression are training-dependent. They belong in the kit when a household member has been trained to use them, and they don’t when no one has.

Most calls to use the kit aren’t going to be trauma though. They’ll be wound care, and the Wilderness Medical Society’s 2014 austere wound care guidelines are the cleanest reference⁸. Irrigate with at least 1 liter of potable or disinfected water at pressure (a 30 to 60 mL syringe with an 18 gauge angiocath does the job). No additives in routine wounds. Close clean, low-tension wounds within 8 to 12 hours, up to 24 for the face, with adhesive closure strips or tissue adhesive. Sutures and staples belong in trained hands, not a kitchen. Pack contaminated wounds open and watch them. AAFP evidence is clear that plain white petrolatum is equivalent to triple antibiotic ointment for routine wound aftercare, with less contact dermatitis and less selection pressure on resistant flora⁹. The kit version: petrolatum, non-adherent dressings, gauze rolls, adhesive strips, tissue adhesive, sterile gloves. Teach the household what infection actually looks like: spreading erythema, streaking, purulence, fever, increasing pain.

Burns are the injury most under-prepared for, and the field guidance has changed. The American Burn Association and the 2025 Annals of Emergency Medicine literature now support 20 minutes of cool running water (not ice, not butter) within 3 hours of injury, with measurably better outcomes¹⁰. Cover with a non-adherent dressing or plastic cling wrap. Hydrogel burn dressings are a field-acceptable third option per ABA, distinct from the older silver sulfadiazine cream that’s no longer first-line. The household version of “what to do with a burn” is simpler than what most of us grew up teaching: water, time, clean cover.

Splints, briefly. One 36-inch SAM splint covers the realistic home use case. Radiolucent, reusable, immobilizes wrist, forearm, ankle, and cervical spine when folded. Add a triangular bandage and a couple of ACE wraps. 

One frame to hold through the rest of this: kits scale with capability. A household with a trained member can credibly carry a higher-tier kit. The category is appropriate medical preparation, sized to capability.


Water and sanitation

Back to fundamentals here. In austere medicine, dehydration is the leading preventable cause of death, and sanitation failures drive much of the rest. The kit answer for both is cheap and simple.

Start with safe water. Ready.gov’s anchor is 1 gallon per person per day¹¹. Treat the source with whatever you have available. Boiling for 1 minute (3 minutes above 6,500 feet) is the gold standard. Unscented household bleach (5 to 9% sodium hypochlorite) works at 8 drops per gallon of clear water or 16 drops per gallon of cloudy water, 30 minute contact time¹². For filtration, the spec that matters is “≤1 micron absolute,” which screens out Giardia and Cryptosporidium; viruses still need chemical disinfection on top.

Then rehydration. The WHO low-osmolarity oral rehydration salt formula (75 mEq sodium, 75 mmol glucose, 20 mEq potassium, 10 mEq citrate per liter) is the standard¹³. Commercial ORS packets are cheap to stock; the home recipe in a pinch is 1 liter of clean water, 6 level teaspoons of sugar, and half a teaspoon of salt. One thing worth telling patients over and over again: adult sports drinks are not pediatric ORS. The sodium is too low and the sugar is too high to treat clinical dehydration in a child, and this really matters when the household has small kids and no power.

Infection prevention is the third leg, and it’s mostly about hand hygiene and a few pieces of PPE. CDC guidance: soap and water for 20 seconds, 60% alcohol hand rub as backup, nitrile gloves (not latex), N95 respirators for smoke and infectious exposure, household bleach for surface disinfection¹⁴. Gloves don’t replace handwashing. We all know to wash our hands. This is the reminder: scrub them, and scrub them well. As basic as it gets, and as load-bearing as anything in the kit.


Power, monitoring, documentation, communication

Four things beyond the supplies themselves. Power: durable medical equipment needs a backup plan. CPAP and BiPAP units run off a portable battery overnight; oxygen concentrators draw too much for that, and the answer is standby tanks, not bigger batteries.

The refrigerator is the harder problem.  I know you’re already thinking about insulin, because the idea of a disaster panics any diabetic patient. Insulin is stable at 59 to 86°F for up to 28 days unopened, per FDA emergency guidance⁴. Do not freeze. Use it warm before going without.


Beyond the insulin window, GLP-1 agonists run 14 to 56 days at room temperature depending on product (Ozempic 56 days at up to 30°C, Trulicity 14)¹⁵. Most injectable biologics fall in a similar window. The point a patient needs to hear in the office, before a hurricane forecast lands: check the package insert for the room-temp tolerance of their specific medication, pack a cooler with ice packs (not direct contact), and don’t freeze any of it.

Monitoring: a thermometer, a validated home blood pressure cuff, a glucometer for diabetics, and a pulse oximeter cover the household use case, with the FDA Safety Communication caveat that pulse-ox devices overestimate true saturation in darker-skinned patients¹⁶. Skip the otoscope; non-clinicians can’t reliably interpret what they see. 

Documentation: the patient’s kit should include a written med list with doses, an allergy list, photos of every pill bottle (the label itself is a functional clinical document), insurance and immunization records, an advance directive, and recent labs on a thumb drive. HIPAA doesn’t block emergency disclosure¹⁷. 

Communication: four pre-emergency setups worth pushing at a routine visit. Patient portal credentials stored somewhere accessible, the prescriber’s direct line saved, a regional telehealth fallback identified before the season, and a backup ER chosen if the usual system is overwhelmed.


Pediatric, mental health, household specifics

A generic kit doesn’t fit a specific household. Here’s a few specific populations who need specialized resources in an emergency. 

Pediatric. Weight-based dosing for acetaminophen, ibuprofen, diphenhydramine, and ondansetron printed on a card the household can read at 2am¹⁸. Pediatric ORS, not adult sports drinks. Ready-to-feed formula in any household with an infant; powder requires safe water that may not be available. Children’s medication doses can be improvised from adult bottles sometimes if truly needed, but beware your numbers: the math is the most common error in field pediatric care.

Mental health. Continuity of psychiatric medications is the under-discussed half of disaster planning. SSRIs, mood stabilizers, antipsychotics, and benzodiazepines: discontinuation syndromes and decompensation are the predictable failure modes when an evacuation runs longer than the on-hand supply. The Schedule II hardship from Module 1 lives here too; stimulants and opioids are the gap. Brief acute insomnia in a sheltered population is expected and self-resolves; eye masks and earplugs are kit items worth recommending.

Pregnancy. A pregnant patient needs an earlier evacuation trigger, a clean emergency birth kit, and prenatal vitamins added to the chronic supply per ACOG¹⁹.

Older adults on polypharmacy need indications named on the med list, not just drug names, plus spare hearing-aid batteries and glasses.

A dental emergency kit (Dentek temporary filling, clove oil, ibuprofen-acetaminophen combo) covers most field dental needs; antibiotics for systemic signs only, ER for swelling extending under the tongue or to the eye.


Capability, and the cliff

A kit you don’t know how to use is decoration. The previous five modules describe the contents of a household’s medical preparation; this one describes what makes that preparation actually work.

Capability is training. Stop the Bleed certification, a basic wound care class, comfort with the medications in the kit, a household conversation about who in the family knows what. Most of this is free or close to it. None of it gets done if we as the clinician haven’t said it out loud during a routine visit.

Which brings us to the cliff.

Patients are figuring this out themselves. They are Googling at 1am and going down Reddit rabbit holes. They are taking dosing advice from prepper forums because the clinical voices have stayed quiet. Healthcare’s collective response to “what should I reasonably have on hand?” has been to hedge or say, ‘you can’t have any prescription on hand ahead of time. That’s not responsible. You’ll be treated only after you need it”. 

The void doesn’t stay empty; somebody fills it.

The failure is at the category level. We never named the thing the patient was asking about, so we never built the framework for thinking about it. The category has a name now: appropriate medical preparation. The framework is the five modules above. The work is making sure the patients in our practices encounter our voice in this space before they encounter someone else’s.

A few of us are charting the grey area in public. We are publishing the criteria, the dosing thresholds, the kit composition, the indications, and the limits, week after week, so that what a curious patient finds when they search is a clinician’s framework rather than a forum’s. This is the work Jase exists to do. If you have patients asking the SHTF question and you want a clinically rigorous resource to point them to, we work with HCPs directly. The goal is not to sell to your patient. It’s to make sure your patient has the guidance of clinical help in this emerging area.


Sources

  1. Greenough PG, Lappi MD, Hsu EB, et al. Chronic Disease and Disasters: Medication Demands of Hurricane Katrina Evacuees. American Journal of Preventive Medicine. 2007;33(3):207-210. PubMed: 17826580.
  2. Ready.gov, Build A Kit (3-day baseline). ready.gov/kit
  3. Healthcare Ready, A Review of State Emergency Prescription Protocols; supporting disaster medicine literature on 30 to 90 day chronic-medication supply.
  4. FDA, Information Regarding Insulin Storage and Switching Between Products in an Emergency.
  5. DEA Pharmacist’s Manual; Healthcare Ready, Review of State Emergency Prescription Protocols (Schedule III through V emergency dispensing coverage varies by state).
  6. American College of Surgeons / Stop the Bleed, kit composition and CoTCCC-listed contents.
  7. Goolsby C, et al., skill-retention data on Stop the Bleed training (the underlying evidence base for the 1 to 2 year refresh recommendation).
  8. Wilderness Medical Society, Basic Wound Management in the Austere Environment (2014 practice guidelines).
  9. American Academy of Family Physicians, wound care evidence: petrolatum vs. triple-antibiotic ointment.
  10. American Burn Association field guidance; Annals of Emergency Medicine (2025), Cool Running Water as a First Aid Treatment for Burn Injuries. PubMed: 40985917.
  11. Ready.gov, Build A Kit (water anchor: 1 gallon per person per day). ready.gov/water
  12. CDC, Making Water Safe in an Emergency; CDC water filtration guidance (the ≤1 micron absolute filter spec for Giardia and Cryptosporidium).
  13. World Health Organization, Oral Rehydration Salts: Production of the new ORS.
  14. CDC, Guidelines for Personal Hygiene During an Emergency; supporting CDC respiratory protection and wildfire smoke guidance for N95 use.
  15. GLP-1 manufacturer prescribing information (Novo Nordisk for Ozempic, Eli Lilly for Trulicity, current US labeling).
  16. FDA Safety Communication: Pulse Oximeter Accuracy and Limitations (2021, updated 2022).
  17. ASPR-TRACIE, HIPAA and Disclosures in Emergency Situations fact sheet.
  18. AAP pediatric dosing charts (acetaminophen and ibuprofen); Lexicomp Pediatric and Harriet Lane (diphenhydramine and ondansetron weight-based dosing).
  19. American College of Obstetricians and Gynecologists Committee Statement No. 15 (January 2025): Preparing for Disasters: Addressing Critical Obstetric and Gynecologic Needs of Patients.

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For Clinicians | Azithromycin (Z-Pack): Why It Earns a Place in Appropriate Medical Preparation

For Clinicians | Azithromycin (Z-Pack)

Why It Earns a Place in Appropriate Medical Preparation

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Edited and approved by Kristen Carpenter, PA-C — Clinical Advisory Board Member

Can’t you just call in a Z-Pack?

Your patients probably ask for one all the time. They know it works, and almost everyone has taken one at some point in their life.

Today we’re talking about the Z-Pack and why it’s so helpful for appropriate medical preparation across a number of different common conditions. What it’s approved to treat. What it’s actually being used for. And where the line sits between what’s okay for a patient to keep on hand and what still needs to be seen by a doctor.


What is azithromycin, and what does it treat?

Azithromycin is a macrolide antibiotic, FDA-approved for a number of common bacterial infections.¹ Most courses run 3 to 5 days, with one-time single-dose regimens for a few specific indications.

A few things make it useful when access to care is delayed:

  • The course is short. The drug accumulates in tissue and has a prolonged terminal half-life, which clinically supports a short course providing antimicrobial activity beyond the dosing window.²
  • It covers the common community-acquired pathogens behind respiratory infections, skin and soft tissue infections, certain sexually transmitted infections, and traveler’s diarrhea.¹
  • It’s a real option for patients who can’t take penicillin, which is a larger group than most clinicians realize.
  • It’s oral, well-tolerated, and inexpensive.

FDA-approved indications include:¹

  • Acute bacterial sinusitis
  • Acute bacterial exacerbation of chronic bronchitis (mild to moderate)
  • Community-acquired pneumonia (mild severity, suitable for outpatient oral therapy)
  • Pharyngitis and tonsillitis as an alternative to first-line therapy in penicillin-allergic patients
  • Uncomplicated skin and skin structure infections
  • Urethritis and cervicitis due to Chlamydia trachomatis or certain gonococcal infections
  • Genital ulcer disease due to chancroid
  • Acute otitis media in pediatric patients

Guideline-supported uses outside the FDA label:

  • Traveler’s diarrhea, particularly in regions where fluoroquinolone-resistant Campylobacter is common (notably Southeast Asia).³
  • Pertussis treatment and post-exposure prophylaxis.⁴
  • MAC prophylaxis in HIV patients with CD4 <50 not on effective ART, and as part of combination treatment for disseminated MAC.⁵

Why azithromycin is in the JaseCase

We here at Jase provide, ahead of time, the medications patients need for a number of emergencies, and azithromycin is one of our favorites.

When a patient picks up a prescription at their regular pharmacy, the clinical work has already been done: the diagnosis is confirmed, the indication is documented, the dosing is verified, and the pharmacist is two steps from the prescriber if anything looks off. Contingency stocking removes all of those backstops. The protocol, the indication match, the dosing, the dispensing instructions, and the patient education all have to be locked before the bottle goes on the shelf.

Jase is in a unique position to help patients proactively. We prescribe for a select set of emergencies, before they happen, at the same clinical standard a patient would receive in the room. Azithromycin earns its place in the JaseCase against a specific set of criteria for contingency use:

Indication breadth. One molecule covers the common community-acquired infections a patient is most likely to encounter outside business hours: a sinus infection that goes brutal on day three, a respiratory infection that won’t quit, a strep-positive kid who can’t take amoxicillin, a chlamydia exposure that needs treating, traveler’s diarrhea that hits halfway through a trip. Stocking one drug that addresses several presentations is more useful in a kit than stocking five drugs each addressing one.

Fixed, short dosing. A 3 to 5 day course with no titration, no renal dose adjustment in the typical adult, no requirement for serum levels, and no repeat dosing decisions. The course we wrote ends when the package ends.

Penicillin alternative. About 10% of the U.S. population carries a documented penicillin allergy on their chart.⁶ The true IgE-mediated rate is closer to 1%, but the labeled-allergy patients still avoid penicillin-class drugs in real practice because confirming the true rate requires testing most patients haven’t had. Amoxicillin-clavulanate is the other common kit antibiotic, and for roughly one in ten patients it isn’t an option. Azithromycin is.

Familiarity that reduces error. Roughly 10.3 million prescriptions for azithromycin are written every year in the U.S., making it the 64th most-commonly prescribed medication in the country.⁷ The patient has likely taken it. The prescriber writes it from muscle memory. The protocol Jase delivers with the kit slots into a pattern both already know. Familiar drugs are safer drugs in contingency use.

Storage and stability. Tablets, room temperature, multi-year shelf life. The drug stays viable in a kit on a shelf at home or in a glovebox on the road.

This is how we treat all the drugs in our JaseCase. They’re very carefully selected.


Azithromycin at a glance

The view for the indications most likely to come up when a patient reaches for their kit. Doses are adult standard unless noted.

Don’t reach for azithromycin for:

  • Viral upper respiratory infections. Antibiotics don’t help. Symptomatic care.
  • Suspected gonorrhea. CDC now recommends ceftriaxone monotherapy; azithromycin is no longer routinely added.⁸
  • Suspected MRSA skin or soft tissue infections.
  • Anything escalating: high fever, sepsis signs, immunocompromise, hemodynamic instability, or systemic involvement.
  • Bacterial infections where a beta-lactam is first-line and the patient is not actually penicillin-allergic. Use the right tool.

Two cautions worth flagging:

  • QT prolongation. Use caution in patients with known QT prolongation, electrolyte derangements, or concurrent QT-prolonging medications.⁹
  • Macrolide resistance. Pneumococcal macrolide resistance is significant and varies by region. For pneumonia in particular, current resistance patterns matter for empiric choice.

Stewardship is the bar, not the brake

The answer is the clinical work that happens before the bottle ever ships, while the situation is still calm and considered. For contingency stocking, the prescriber isn’t going to see the patient at the moment of use, so the screening has to be stricter on the front end, not looser. We review the patients current medical conditions, medications, and any allergies they may have to determine if the case medications would be safe for them to take. Patients complete an intake and attestations, a licensed prescriber reviews them against those criteria, and the kit ships only when the fit is appropriate. The patient isn’t reaching into the cabinet on instinct. They are reaching for a medication a prescriber already cleared for them, before they ever got sick.


Each medication in the kit ships with an information sheet: basic drug information, common side effects, contraindications, and dosing for common conditions. The sheets aren’t a diagnostic tool. They are reference materials patients can use to follow the prescriber’s plan and bring accurate information into the room if they end up in front of another clinician. Our team can answer clarification questions about how the medications work. We are not the patient’s treating clinician, and the kit is not a substitute for primary care.

Contingency stocking in this category needs to clear a higher stewardship bar than routine office prescribing, not a lower one. The patient is going to be at home, at a campsite, on a cruise ship, in a hotel halfway across the world, somewhere the prescriber can’t see them. That changes the protocol design. It does not relax it.


Who makes these calls

Our team is medical doctors, physician assistants with field experience in disaster medicine and humanitarian response, and pharmacists. The clinical work happens on the front end, so the patient isn’t doing it alone at 11pm.

Kristen Carpenter, PA-C, put it this way when we mapped out the JaseCase formulary:

When we decided which antibiotics belonged in the JaseCase, azithromycin was an easy choice. It’s a broad-spectrum antibiotic that can treat a number of different bacterial infections. It is fast acting, usually requires shorter treatment courses, compared to other antibiotics, and is a great alternative for people who are allergic to, or cannot get, penicillin, offering a necessary backup in a limited-supply scenario.


Charting the grey area in public

Contingency stocking for predictable, common emergencies is a real clinical category, and the guidelines haven’t caught up to it yet. Our team is publishing how we make these calls, the criteria we use to add or exclude a drug, and the protocols we deliver with each kit.

If a patient keeps asking and you’d rather not take on the contingency work yourself, you can refer them to us at Jase.com. It’s a clinical handoff, not a product pitch.

Public knowledge gets better when clinicians chart the grey area in public instead of letting the internet do it. The category is going to fill in. The question is who fills it in, and with what standard.


The bottom line

Azithromycin earned its place in the JaseCase on clinical merit: indication breadth, short fixed-course dosing, a real penicillin alternative, familiarity, and shelf stability. The same screen applies to every drug we add. This is not a replacement for primary care. It is the bridge for the moments primary care isn’t there. Trusted medicine, on your patient’s shelf, before the moment they need it.

To learn more, check us out at Jase.com.


Sources

  1. FDA Zithromax (azithromycin) prescribing information. Indications and Usage; Dosage and Administration. DailyMed: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=db52b91e-79f7-4cc1-9564-f2eee8e31c45
  2. FDA Zithromax (azithromycin) prescribing information, Clinical Pharmacology section (pharmacokinetics: tissue distribution and prolonged terminal half-life). Same DailyMed reference as #1.
  3. CDC Yellow Book, Travelers’ Diarrhea chapter. Azithromycin first-line empiric treatment in Southeast Asia and other regions with fluoroquinolone-resistant Campylobacter. https://www.cdc.gov/yellow-book/hcp/preparing-international-travelers/travelers-diarrhea.html
  4. CDC. Pertussis (Whooping Cough): Treatment and Post-Exposure Prophylaxis. https://www.cdc.gov/pertussis/hcp/clinical-care/index.html (treatment overview); https://www.cdc.gov/mmwr/pdf/rr/rr5414.pdf (MMWR RR-54/14, 2005, for dosing).
  5. NIH/CDC/IDSA. Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV: Mycobacterium avium Complex. Azithromycin is the preferred agent for primary prophylaxis (CD4 <50 not on effective ART) and a preferred first agent as part of combination treatment for disseminated MAC. https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/disseminated
  6. CDC. Evaluation and Diagnosis of Penicillin Allergy for Healthcare Professionals. ~10% of U.S. patients report a penicillin allergy; <1% are truly allergic. https://www.cdc.gov/antibiotic-use/hcp/clinical-signs/index.html. Supporting: Castells M, Khan DA, Phillips EJ. “Penicillin Allergy.” N Engl J Med 2019;381:2338-2351.
  7. ClinCalc DrugStats Database. Azithromycin: estimated 10,337,595 U.S. prescriptions (2023), ranked #64 among the most-commonly prescribed medications. https://clincalc.com/DrugStats/Drugs/Azithromycin
  8. CDC Sexually Transmitted Infections Treatment Guidelines, 2021. Gonococcal infections: ceftriaxone monotherapy (500 mg IM single dose for patients <150 kg). Azithromycin is no longer routinely added to dual therapy. Chlamydial infections: doxycycline 100 mg BID x 7 days is the recommended regimen; azithromycin 1 g single dose is listed as an alternative. https://www.cdc.gov/std/treatment-guidelines/gonorrhea-adults.htm and https://www.cdc.gov/std/treatment-guidelines/chlamydia.htm
  9. Ray WA, Murray KT, Hall K, Arbogast PG, Stein CM. “Azithromycin and the Risk of Cardiovascular Death.” N Engl J Med 2012;366:1881-1890. FDA Drug Safety Communication, March 2013: azithromycin QT prolongation risk. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-azithromycin-zithromax-or-zmax-and-risk-potentially-fatal-heart. Current Zithromax label includes QT prolongation in Warnings.

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For Clinicians | Natural Disaster Preparedness: The Medical Framework Most Emergency Kits Miss

For Clinicians | Natural Disaster Preparedness

The Medical Framework Most Emergency Kits Miss

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Edited and approved by Kristen Carpenter, PA-C — Clinical Advisory Board Member


Are families actually prepared for natural disasters?

Most aren’t. Not because they don’t care. Not for lack of being told to prepare. We prescribers haven’t done the proactive work. Families don’t know what they actually need on hand, or what to prepare for medically.

A 72-hour kit and a flashlight aren’t a medical plan. A bandage and a bottle of Tylenol aren’t a medical plan. Prescriptions and medical supplies are the part most checklists skip. We prescribers have to make sure that part is right.

This article is that framework. It pulls together the patient-facing components Jase has been building for years: the 72-hour kit, the family communication plan, and wound care. The clinical layer sits on top of all three.


Most of us had a lecture on disaster medicine. Few of us had to use it.

Pharmacy school, medical school, PA school all covered it. A slide deck, maybe a chapter on triage in a mass-casualty event. Then we moved on. Most of us didn’t think about it again until it was actively happening to a patient, or to us.

That’s the muscle we’re training now, and it has to cover more than the big ones. Two categories matter here.

Natural disasters are usually few and far between for individual families, but of epic proportions when they happen. Evacuation across state lines at 2am because of a wildfire. Pharmacies underwater for a week after a flood. An earthquake that closes the only urgent care in the county. The ER two counties away after a hurricane knocks out the closer ones. These are the ones that make the news. The families who do well didn’t assume the system would be there afterward. They got medically ready before the storm had a name.

Situational disasters are the everyday version. The disaster isn’t the weather. It’s the access gap itself. The patient who lives 90 minutes from urgent care and gets a UTI on a Friday night. The family on a cruise when a kid spikes a fever and the nearest English-speaking pharmacy is closed. The traveler whose refill won’t arrive before the flight. The toddler whose ear infection announces itself at 11pm on a Saturday in a town with no 24-hour pharmacy. These don’t make the news. They happen every week, to most of our patients. They hit the same access gap as the natural disasters. Just smaller.

The framework has to serve both. Our patients don’t have time to wait while we figure it out in the moment. The job is to think proactively. Build the framework once. Have a ready answer for what they need, before they need it.

Patients are already figuring it out on their own. Prepper internet, TikTok dosing advice, online forums, the friend-of-a-friend who knows a guy. When clinicians don’t chart this space, the internet does. The answers patients find range from reasonable to reckless.


What medication readiness actually looks like

Two layers, both clinical. The first keeps the patient’s current regimen intact. The second covers what the disaster predictably brings.

Layer 1: Chronic continuity
Every patient with a chronic medication needs at least a 90-day supply on hand. Insurance vacation overrides and mail-order fills are the standard mechanisms; coverage varies by state and insurer.

The written medication list is the second half. It is the part that gets skipped most often. Keep one page on the patient or in their go-bag. List every medication by name, dose, prescribing physician, and the pharmacy that actually fills it. With that list in hand, a pharmacist who’s never seen them before can help them so much more easily. Without it, the patient is trying to remember their own regimen under stress.

Layer 2: Acute contingency
This layer covers what the disaster predictably causes.

When water and sanitation fail, GI infections spike. When evacuation shelters fill up, skin and wound infections follow.1 UTIs don’t pause for the storm. Respiratory exacerbations get worse in smoke or mold. Pediatric ear infections happen on the same Saturday night they always do. This time, in a town where the 24-hour pharmacy just closed. These are predictable conditions with well-defined treatment paths. They don’t need a new clinical decision in the moment. They need access in the moment.

That means a prescription contingency layer. Antibiotics for the UTI, skin, respiratory, and GI infections disasters predictably cause. Anti-emetic, anti-diarrheal, and oral rehydration for when IV access isn’t on the table. The JaseCase covers this. A clinician prescribes ahead, evaluates the patient’s history, and counsels on appropriate use.

Think of it this way. Telehealth already prescribes for most of these conditions reactively. Layer 2 is the same prescribing, moved earlier in the timeline. The decision tree is short. The evidence base is solid. The medication ends up with the same patient either way. The only thing that changes is whether they have it when they need it.


What disasters predictably cause, and what to have ready

Different disasters drive different clinical needs. The pattern is consistent enough to build a reference you can carry into the room:

Disaster type Predictable medical needs
Wildfire / smoke event Respiratory exacerbations, eye irrigation, refill disruption
Flood / hurricane GI infections from contaminated water, skin and wound infections, mosquito-borne, mold-triggered respiratory
Earthquake / tornado Traumatic injuries, debris wounds, crush, contamination, local mass-casualty triage
Extended power loss Insulin and refrigerated medications, CPAP and oxygen disruption, heat illness
Extreme heat Heat exhaustion and heatstroke, dehydration, cardiac and respiratory exacerbation, medication temperature instability
Winter storm / extreme cold Hypothermia, frostbite, CO poisoning from indoor heating workarounds, refill and supply disruption

The prescription contingency layer maps cleanly onto this:

  • Skin and wound infections: amoxicillin-clavulanate, doxycycline, clindamycin
  • GI infections from contaminated water: ciprofloxacin, TMP-SMX, metronidazole
  • UTIs (which happen disaster or not): ciprofloxacin, TMP-SMX
  • Broad-spectrum for high-contamination wounds: amoxicillin-clavulanate, doxycycline

The point of the table is not to memorize coverage. It’s a quick reference for what to keep an eye out for, given the disaster type most likely in your area. A clinician in coastal Florida prepares a different list than one in tornado country or wildfire county.

 


Beyond the prescription layer: the survival-medical basics most kits get wrong

Three pieces patients consistently under-pack:

  • Water. A filter that handles both viruses and bacteria, not just bacteria. Most consumer filters miss viruses.2 Add a chlorine or boiling protocol the family has actually practiced.
  • Wound care. Most wounds heal without antibiotics. Clean with tap water and soap. Keep moist with petroleum jelly, not OTC antibiotic ointment.3 Then monitor. Prophylactic antibiotics matter for contaminated wounds, non-potable water exposure, bites, sensitive locations, and patients who are diabetic or immunocompromised.4.
  • OTC. Pain, fever, allergy, anti-emetic, anti-diarrheal, and oral rehydration. The standard kit skews toward pain and antacids. Anti-emetic and oral rehydration are the missing pieces.

The category has a name: appropriate medical preparation. It covers self-limiting, predictable, well-understood conditions. Prescribing ahead is clinically identical to prescribing at the moment.


Charting this grey area in public

Jase’s team includes board-certified family medicine physicians. Our physician assistants have field experience in disaster medicine and humanitarian response. The clinical work happens on the front end. The patient isn’t doing it alone at 11pm in a town where urgent care just closed.

Public knowledge gets better when we chart the grey area in public. Otherwise, the internet does it for us. If you don’t have bandwidth to build a medical readiness plan in the room, you can refer patients to us at Jase.com. We’ll keep sharing frameworks and decision criteria here as we go.

We link three patient-facing guides below. They cover the 72-hour kit, the family communication plan, and wound care. The JaseCase covers the prescription contingency layer for families who want to go further. FirstAid sits alongside it for wounds and injuries. Bunker in a Box handles the longer haul. None of this replaces primary care. It exists for the times primary care isn’t reachable.


Sources

  1. Centers for Disease Control and Prevention. “Vibrio Illnesses After Hurricane Katrina, Multiple States, August–September 2005.” MMWR Morb Mortal Wkly Rep. 2005;54(37):928-931. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5437a5.htm
  2. Centers for Disease Control and Prevention. “About Water Treatment Options When Hiking, Camping, or Traveling.” Drinking Water Prevention guidance, 2025. https://www.cdc.gov/drinking-water/prevention/water-treatment-hiking-camping-traveling.html
  3. Smack DP, Harrington AC, Dunn C, et al. “Infection and Allergy Incidence in Ambulatory Surgery Patients Using White Petrolatum vs Bacitracin Ointment: A Randomized Controlled Trial.” JAMA. 1996;276(12):972-977. https://jamanetwork.com/journals/jama/article-abstract/408314
  4. Stevens DL, Bisno AL, Chambers HF, et al. “Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America.” Clin Infect Dis. 2014;59(2):e10-e52. https://academic.oup.com/cid/article/59/2/e10/2895845
  5. Centers for Disease Control and Prevention. “What to Do After a Hurricane or Flood: Mosquitoes.” https://www.cdc.gov/mosquitoes/response/index.html
  6. Centers for Disease Control and Prevention. “Use of Carbon Monoxide Alarms to Prevent Poisonings During a Power Outage, North Carolina, December 2002.” MMWR Morb Mortal Wkly Rep. 2004;53(09):189-192. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5309a1.htm

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For Clinicians | World Cup 2026 Pre-Travel Counseling

For Clinicians | World Cup 2026 Pre-Travel Counseling

Three Host Countries, Three Measles Outbreaks

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Edited and approved by Kristen Carpenter, PA-C — Clinical Advisory Board Member

By the time a patient is in your exam room asking about MMR before a Mexico City group stage match, or whether the dengue notice applies to their cruise out of Galveston, they’ve already done the easy googling the answer online. The basic question doesn’t require a visit with you.

What lands on your schedule now is the second-layer question. The one they couldn’t find a good answer to online.

Most of us were having a different conversation with travelers five years ago. Pre-travel counseling mostly isn’t reaching a provider at all. Patients are searching, asking AI, scrolling forums, and going. The ones who do bring it to you are bringing the residual question, the one the internet didn’t resolve cleanly. Often it’s a very specific recommendation they want: do I actually need this booster, what should be in the kit, etc. This article is meant to be the clinician-side reference for the summer 2026 version of that conversation.


What’s actually on the CDC board for summer 2026?

The World Cup is the biggest thing happening this summer around the world. Measles is active in all three World Cup host countries. The US has confirmed 1,952 cases as of late May, already approaching the full-year 2025 total of 2,288 with the entire summer ahead.¹ Canada lost its measles elimination status in November 2025 after twelve months of sustained transmission and has reported 907 new cases since the start of 2026.² Mexico’s Jalisco state, home of World Cup host city Guadalajara, has logged 5,282 confirmed cases through mid-April in the country’s worst outbreak in decades.³ Guadalajara isn’t a measles statistic, it’s a place your patients are booking flights to.

The CDC has issued a Level 1 Global Dengue notice covering more than 100 countries, which is an unusually broad advisory.⁴ Locally acquired dengue is also showing up in southern US cities, with multiple confirmed cases in Los Angeles County over the past two transmission seasons.⁵

A novel hantavirus cluster on the MV Hondius expedition ship in the South Atlantic killed three passengers in May, identified as Andes virus.⁶ The WHO assessed the global risk as low. More on the cruise question below.

And the World Cup itself is the largest funnel event in the history of international travel: 48 teams, 16 host cities across the US, Mexico, and Canada, and FIFA’s projected engagement figure of nearly 6 billion people.⁷ You’re thinking: most of them will be watching from a couch. True. But millions will not.


Quick reference: summer 2026 by destination

A pull-up-in-the-room reference for the most common itineraries your patients are flying.

World Cup host countries (US, Canada, Mexico). Active measles transmission in all three. Verify MMR status, especially for adults born after 1957 with uncertain documentation. Patients vaccinated between 1963 and 1968 may have received the inactivated vaccine and should be revaccinated. Check the CDC measles notice before departure.

Caribbean, Latin America, and the southern US. Dengue is elevated in 2026 across Cuba, Brazil, Colombia, Mexico, and locally in southern California and along the Gulf. Counsel EPA-registered repellent (DEET or picaridin), permethrin on clothing, and air-conditioned or screened sleeping. Tell patients to seek care if a fever spikes within two weeks of return.

Cruise ships. The cruise ship hantavirus story is everywhere this month, and it deserves a one-line answer: your patient’s Caribbean cruise out of Miami is statistically not where this is happening. The MV Hondius cluster was on an Antarctic expedition vessel, geographically remote, and WHO has assessed the global risk as low. The actual cruise ship risk is much more mundane….and much more likely. Norovirus is the leading cause of cruise ship outbreaks, and a separate norovirus event affected hundreds of passengers on a Caribbean cruise this same month. The other reliable ways to lose a cruise day: respiratory virus, traveler’s diarrhea, motion sickness. Counsel aggressive handwashing (alcohol gel works against respiratory viruses but soap and water is what handles norovirus), pack a small kit, and report symptoms early so the cruise medical staff can manage them in the cabin instead of letting them derail the trip.


The 20-minute checklist

Four steps, and it fits inside a short visit.

 

  1. MMR verification. For adults born after 1957, confirm two documented doses or evidence of immunity. Adults born before 1957 are generally considered immune. Patients vaccinated between 1963 and 1968 may have received the inactivated vaccine and should be revaccinated. (Your MA can pull these records in five minutes. It doesn’t need to be your time.)
  2. CDC notices for the specific destination. Send patients to the CDC Travelers’ Health page for their destination. The notices update frequently. The page is at wwwnc.cdc.gov/travel/notices.
  3. Medical prep, not just medications. The kit conversation is broader than prescriptions. The prescription backbone is one piece. The rest is the simple stuff that keeps a small problem from becoming the thing they remember about the trip. A reasonable kit, paperback-sized, fits in a carry-on:
  • Gauze and adhesive bandages in two sizes
  • Antibiotic ointment (Neosporin or equivalent)
  • Blister care: moleskin and hydrocolloid patches
  • Oral rehydration salts or electrolyte packets
  • A digital thermometer
  • OTC motion sickness medication
  • A short course of clinically appropriate prescription medications for predictable conditions like UTI, traveler’s diarrhea, common respiratory infections, and yeast infections. This is what Jase handles, prescribed and packaged ahead of the trip.

The kit exists so your patient doesn’t end up standing in a foreign pharmacy at 9pm with a phone translator trying to figure out which Spanish word means antiseptic.

4. What’s available at a foreign pharmacy, and what isn’t. Pharmacy availability varies more than patients expect. Some countries dispense antibiotics over the counter. Others require a domestic prescription that a US script won’t satisfy. Brand names you trust at home may carry different active ingredients abroad, or different doses. View our recent article on Prescription Medication Abroad.


The OTC trap when you’re abroad

This sounds boring and obvious, but is the highest-leverage thing a clinician can teach a traveling patient.

 

Over-the-counter in another country does not mean equivalent to over-the-counter at home. Acetaminophen is sold as paracetamol in most of the world; dosing is usually the same, but the name swap leads to accidental double-dosing when patients also take a combination cold medication that contains the same active ingredient. Ibuprofen is available widely, but the dose per tablet varies. Antihistamines sold under familiar US brand names abroad sometimes contain different active ingredients, including older sedating compounds that can interact with travel sedatives or alcohol. Counterfeit medication is a real concern in some regions and includes products with the wrong dose, the wrong drug, or no active ingredient at all.

 

The rule we counsel: bring what you already use, in the dose you already use. Foreign pharmacies are useful for things you didn’t anticipate, not for things you could have packed.


When the call comes from abroad

Your patient is on day four of a Caribbean cruise with a UTI that started in Cozumel. Or she’s in Florence with a sinus infection she’s been ignoring since Rome. Or he’s on a two-month sabbatical and the antifungal he meant to refill before he left got missed. The portal message comes in. The voicemail comes in. The text from the family member who has your cell. The expectation is that you’ll fix it from your desk.

You can’t.

As Kristen put it to me when we were drafting this together: “I can’t send a script to Europe.”

That’s the first wall. There is no mechanism for routing US prescriptions to foreign pharmacies. And even within the US, looking up an out-of-state pharmacy in eScript takes a while. It’s doable; just a pain that takes up precious time between patients.

The second wall is bigger: anticipating everything that could come up across a two-week trip. The sinus infection that builds on the flight. The GI bug that hits day three. The skin issue from the cruise pool. The allergic reaction to something at a night market. Half a dozen potential prescriptions across as many therapeutic categories, for conditions that may or may not actually present. That work is complex, isn’t part of your fast clinical workflow, and takes hours, not minutes, per patient. Unless you’ve got a really standardized protocol covering all the categories, it’s just easier to refer. It can be done. It probably just doesn’t feel worth your time.

The known versus the unknown is the real divide here. Writing one or two prophylactic scripts for a patient with a recurring issue you already know about (the UTI history, the predictable cold sore) is something most providers can do confidently. The indication is clear, the duration is short, the patient self-identifies. Anticipating everything that might come up on a trip is hard. It should be hard, because it’s very complex.


Appropriate medical preparation

This is the category Jase is building, and pre-travel readiness is one of its clearest applications. Appropriate medical preparation means a short list of well-defined, common, predictable conditions handled clinically before the patient is sick, by people who know what they’re doing, so the patient has what they need before they need it.

It is in no way a replacement for primary care. Complex diagnoses, chronic conditions, ongoing provider relationships belong in your exam room. We work in the contingency space: the UTI on day four of the trip, the traveler’s diarrhea on day six, the strep that announces itself the night before a flight home. The conditions where the clinical decision is predictable and the only failing variable is access.

This is a call to prepare appropriately, not exhaustively.


Who’s doing this work

Jase is a family company of medical doctors, physician assistants, and pharmacists, five years in, with the credentials breadth (board-certified family medicine, disaster medicine, multi-state pharmacy) to make the clinical work defensible.


Charting the grey area in public

Pre-travel counseling is a capacity problem in most primary care practices. The visit is short, the destinations are varied, the CDC board changes faster than most providers can track. If your patients are asking and you don’t have the time to walk them through it, you can refer them to us at Jase.com. We handle the prescription work, the kit, and the patient education ahead of the trip, and we send them back to you with documentation.

We’re going to keep publishing the framework as we use it. The clinical decision trees, the destination-specific notes, the cases where the call is harder than it looks. Public knowledge gets better when clinicians chart the grey area in public instead of letting the internet do it.


The bottom line

Summer travel is supposed to be exciting. It is not supposed to be anxious.

A verified MMR, a short conversation about the destination’s CDC notice, and a small kit on the shelf will handle the vast majority of what makes a trip go sideways. Most of it is fixable in advance, and the fixing happens in your office or ours, not in a foreign emergency room at 11pm.

If your patient is heading to a host city this summer, send them out the door prepared. If you’d rather refer them, send them to us. Either way, the goal is the same: a trip they remember for the right reasons.


Sources

  1. CDC, “Measles Cases and Outbreaks,” data as of May 21, 2026: 1,952 confirmed cases in the US year to date. cdc.gov/measles/data-research
  2. Gavi VaccinesWork and PAHO: Canada lost measles elimination status November 10, 2025, after sustained transmission. CIDRAP reporting on 907 cases since January 2026.
  3. ABC News, US News, Mexico News Daily reporting on the Jalisco outbreak: 5,282 confirmed cases through April 10, 2026, in Mexico’s worst outbreak in decades.
  4. CDC Travel Health Notices, Global Dengue Level 1: wwwnc.cdc.gov/travel/notices/level1/dengue-global
  5. Los Angeles County Department of Public Health; CDC Emerging Infectious Diseases, May 2026, on autochthonous dengue transmission in southern California.
  6. WHO Disease Outbreak News, May 2026; CDC HAN 00528: MV Hondius hantavirus cluster, Andes virus, 7 cases including 3 deaths.
  7. FIFA and TheWorldData on the 2026 World Cup: 48 teams, 16 host cities across the US, Mexico, and Canada; FIFA’s projected engagement figure of approximately 6 billion.

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