For Clinicians | Emergency Prescription Refills and 90-Day Fills

For Clinicians | Antibiotic Eye Drops for Pink Eye

What to Do When a Patient’s Pharmacy Is Closed

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Medically reviewed and edited by Kristen Carpenter, PA-C

“I’m from out of town and I just took my last pill from another pharmacy. Can you give me a refill? I reaaaaally need this med”

I’ve had this happen to me dozens of times every ski season in the mountain town pharmacy I worked at for years. Friday at 4:50pm when all offices are closing up shop for the weekend. People don’t always have the pharmacy closest to them open and ready with their prescriptions. It happens for all sorts of reasons.  A hurricane or a holiday weekend. A staffing shortage that closed the pharmacy early with no sign on the door guaranteeing when they will open again. A power outage. Or the chain closed a batch of locations in one fell swoop when they went under.

Today we’re talking about closed pharmacies, and about how much of this is preventable from our side of the encounter. First, what you can put in place ahead of time so a closed pharmacy is an inconvenience instead of a crisis. Second, what you and your patient can do once the door is already locked and Monday is three days away.

How much medication do your patients actually have on hand?

Here’s how I think about this as a pharmacist. Picture a patient on a 30-day prescription. Their plan lets them refill once they’ve used about 75 percent of it, so somewhere around day 22. Most people go pick it up right then, because that’s when the pharmacy texts them that it’s ready. So they walk out with 30 new pills while a week of the old bottle is still sitting at home. Seven or eight pills, if it’s a once-a-day medication.

That’s the whole cushion. Seven pills. Nobody chose that number. It falls out of a 30-day fill and a refill window, and that’s the only reason it’s seven. If you’re prescribing rather than dispensing, this is the part you never see, because the refill math happens weeks after the patient leaves your office.

Now here’s what bugs me. Nobody agrees on the number. The Red Cross says keep a 7-day supply of medications.¹ The CDC’s own emergency kit checklist says at least two weeks.² FEMA’s Build a Kit page lists prescription medications and never names a number at all.³ Seven days is the one that propagated out to every state and county checklist, and seven days is what the patient already had by accident. The one study I know of that looked at what a household actually needs put the number at 14 to 30 days, and said the way to get there is longer fills.⁴ The CDC is closest to right and nobody is following it.

What to put in place ahead of time

These are workflow changes, not clinical ones. 

  • Default to a 90-day fill on stable chronic medications. Same drug, same dose, same annual quantity. What changes is how often that patient has to stand in a line for it.
  • Synchronize the refill dates. A patient on five chronic medications with five different fill dates is making five trips a month and getting five separate chances to run out on the wrong weekend. Write them all in one visit, aligned to a single date. The AAFP has recommended this for years as practice management, and it’s the same action with a different reason attached.5 Your MA can call the pharmacy to align the first cycle so it doesn’t eat your afternoon.
  • A year is on the table, and most people don’t know it. For chronic medications that aren’t controlled substances, a prescriber can authorize up to a year of a patient’s own validated prescription to fill at a single time. Plenty of prescribers assume that isn’t allowed. Insurance likely will only cover 90 days regardless of what you wrote. It’s something for the patient to ask about, not something to promise them.
  • Put the list on paper. Every medication in the house, with drug, dose, prescriber, and pharmacy. A pharmacist who has never met your patient can work from that list. Without it we’re guessing, and we don’t fill on a guess. Simple solution is to just print their med list from your EMR and give it to the patient instead of having the MA re-write everything by hand.

Can another pharmacy fill your patient’s prescription?

Usually yes, and more easily than most patients expect. Inside a chain, any store can pull up that patient’s prescriptions and fill them. Controlled substances get more complicated, but even then the new store can see the prescription and who wrote it, which is enough to start the conversation.

Outside the chain, it comes down to whether the patient brings the bottle. When someone handed me their bottle from another pharmacy, I could verify the prescription off the label, get them an emergency supply, and call their office Monday for a formal script. Without the bottle, at 8:55 on a Sunday night, there was nothing I could do for them because I couldn’t just take their word for it that they were taking that specific Rx.

So the counseling is four things:

  • Bring the bottle to the pharmacy where you are. The label is what makes verification possible.
  • Call ahead instead of walking in. Five minutes before close is the worst possible time to ask.
  • Give lead time. “I have three pills left” on Thursday morning opens doors that “I’m out” on Friday at 5:59pm does not.
  • Expect to pay cash. Insurance usually won’t process a fill this way, and a patient shouldn’t expect coverage. Great time for a discount card.

Two extra things to know. The first is the 72-hour emergency supply. A pharmacist’s authority to dispense without prescriber authorization varies enormously by state, and a meaningful number of states give pharmacists none at all. Several states that do have public-health-emergency provisions require a governor’s declaration to activate them, so the advice is weakest in the situation patients actually find themselves in: an ordinary Friday, nothing declared, nothing activated. Look up your own state before you tell a patient to count on it.6 It’s really more for epic natural disaster situations.

The second is Schedule II. There is no refill mechanism under federal law, so a patient who runs out on the road needs a new written prescription, not an authorization. A prescriber can verbally authorize an emergency quantity limited to the emergency period, with the written prescription delivered to the pharmacy within days. This is federal, so a state’s emergency dispensing rules don’t create a workaround. For patients on stimulants or opioids, that’s a conversation to have before the trip, not during it.7

Ahead of time there is one thing you can do. Federal rules let you issue multiple Schedule II prescriptions totaling up to a 90-day supply, each one marked with the earliest date a pharmacy may fill it, where your state permits it and where you judge there’s no undue diversion risk.⁷ It isn’t a refill and the regulation is careful to say it isn’t an expectation, but it’s the closest thing these patients have to the 90-day fill everyone else gets.

Everything above is a workaround

Now that we’ve covered the basics, look at what this article has covered. A longer fill, because the default one is too short. A bottle carried to a stranger’s counter, because there’s no other way to verify. A 72-hour supply that depends on which state line your patient happens to be standing behind. Every one of these gets around the same absence. There’s no sanctioned step between reaching a clinician and being on your own with whatever is in the cabinet. Care is all or none. Either your patient gets to someone who can write or verify, or they’re counting seven pills on a Friday night.

That missing step is what we build at Jase, and the category has a name: appropriate medical preparation. For a short list of well-understood conditions, the clinical work happens on the front end. A licensed provider reviews the request and writes the prescription before anything ships, so the patient isn’t hunting for a prescriber at 8:55 on a Sunday night. It’s for emergency use only, after first seeking the assistance of a qualified healthcare provider.

This is in no way a replacement for primary care. Chronic disease management, complex diagnoses, and the ongoing relationship belong with you. What a JaseCase holds is the acute layer a disruption creates, the infection or injury that shows up during the week nobody can reach a pharmacy. The chronic half of the problem is the one you solve, in your office, with the four things in the list above.

If you’d rather refer

Some of you will want to work out the day-supply and standby-prescribing questions yourselves, and you should. Some of you have a full panel and no room for a new category of conversation inside a 15-minute visit or a line at the counter. Either is a reasonable place to land. If it’s the second, send them to us at Jase.com, where one of our licensed providers reviews the request and writes anything prescription that gets filled.

The criteria are the part we owe you. Which conditions qualify, what we decline to prescribe ahead of time and why, and how we handle the cases that don’t fit cleanly. We publish that here as we settle it, so you can argue with it or borrow it.

TL;DR

Patient calls, their pharmacy is closed:

  • Same chain nearby? Any store can pull their profile and fill it.
  • Different pharmacy? Bottle in hand, call ahead, expect cash.
  • Schedule II? No refill exists. New written prescription, or a verbal emergency quantity with the written script following in a few days.
  • No bottle and nobody reachable? A state emergency supply, if your state has one.

Every workaround in this article exists because there’s no sanctioned step between reaching a clinician and going without. We’re building that step and publishing the criteria as we set them. Until it exists, the shortest path runs through the script you write: ninety days instead of thirty, synced to one date, printed on a list your patient can hand to a stranger.


Sources

  1. American Red Cross. Survival Kit Supplies. “Medications (7-day supply) and medical items.” https://www.redcross.org/get-help/how-to-prepare-for-emergencies/survival-kit-supplies.html 
  2. CDC. Emergency Kit Checklist: Pregnant Women, Infants, and Children. Updated April 30, 2026. “Prescription medications (at least 2 weeks supply).” https://www.cdc.gov/children-and-school-preparedness/resources/emergency-kit-checklist-pregnant-women-infants-and-children.html 
  3. FEMA. Build A Kit, Ready.gov. Updated July 1, 2026. Lists prescription medications among additional emergency supplies with no day-supply figure given. https://www.ready.gov/kit 
  4. Carameli KA, Eisenman DP, Blevins J, d’Angona B, Glik DC. Planning for chronic disease medications in disaster: perspectives from patients, physicians, pharmacists, and insurers. Disaster Medicine and Public Health Preparedness. 2013;7(3):257-265. Los Angeles County sample. “Most prescriptions are dispensed as 30-day units through retail pharmacies with refills available after 75% of use, leaving a monthly medication reserve of 7 days.” Health professionals in the study supported 60- to 100-day dispensing units to reach the recommended 14- to 30-day reserves. https://pubmed.ncbi.nlm.nih.gov/23103395/ 
  5. Sinsky TA, Sinsky CA. A Streamlined Approach to Prescription Management. Family Practice Management. 2012;19(6):11-15. The physician renews all of a patient’s chronic medications, excluding narcotics and benzodiazepines, at the annual comprehensive care visit; estimated saving of one to two hours of physician and staff time daily. https://www.aafp.org/pubs/fpm/issues/2012/1100/p11.html 
  6. Healthcare Ready. A Review of State Emergency Prescription Protocols. September 18, 2022. 16 of 51 jurisdictions have no laws or regulations pertaining to emergency prescriptions; 23 allow a general emergency refill; 12 have public-health-emergency-specific provisions, of which 10 activate on a governor’s declaration. More than half of states allow only a 72-hour emergency supply or none at all. https://healthcareready.org/a-review-of-state-emergency-prescription-protocols/ 
  7. 21 CFR 1306.12(a): “The refilling of a prescription for a controlled substance listed in Schedule II is prohibited.” 21 CFR 1306.12(b): a practitioner may issue multiple Schedule II prescriptions totaling up to a 90-day supply with earliest-fill dates marked, where permissible under state law. 21 CFR 1306.11(d): an emergency oral Schedule II prescription is limited to the quantity needed for the emergency period, and the prescriber must cause a written prescription to be delivered to the dispensing pharmacist within 7 days. https://www.ecfr.gov/current/title-21/part-1306

 

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First Aid Kit Essentials: What Every Home and Family Needs

First Aid Kit Essentials: What Every Home and Family Needs

The First Aid Guidelines Changed in 2024. Your Kit Probably Didn’t.

By Aaron Asay, PA-C, DMSc

This is not a shopping trip. It’s a fifteen-minute audit of what’s already in the box under your sink — and for most of it, the action is taking things out.

In 2024, the American Heart Association and the American Red Cross released the first full revision of the first aid guidelines since 2010. Fourteen years. Most of the checklists people find online still reflect the 2010 standard. Most of the kits sold in retail stores still ship with products the updated guidelines no longer recommend. And most households have no idea any of this changed.

There are four things worth knowing.

One: The aspirin dose is not what you think

Here’s the scenario I want you to sit with: someone’s chest hurts at the kitchen table. You’ve heard your whole life that you give them aspirin. So you go to the cabinet and grab the baby aspirin bottle, because that’s the heart one.

The dose in the 2024 guidelines is 162 to 325 milligrams, chewed, not swallowed whole.

That is two to four of those 81mg tablets. For a suspected heart attack, the instruction is: call 911 first. Then give aspirin — 162 to 325mg, chewed. The chewing matters because it speeds absorption. Swallowing a single 81mg tablet whole is not the right action, and plenty of first aid kits don’t contain enough tablets even if you know the correct dose.

Check what’s in your kit. Know the dose before you’re in the scenario.

Two: Hydrogen peroxide and rubbing alcohol don’t belong on open wounds

Both are still packaged in retail first aid kits. Both have been in medicine cabinets for generations because that’s what our parents used. The evidence has moved past them.

Hydrogen peroxide and isopropyl alcohol are cytotoxic to the cells involved in wound healing. Applied to an open wound, they damage the tissue trying to repair itself. The 2024 guidelines are explicit: clean an open wound with soap and clean running water. That’s it. If you have peroxide in your kit, take it out. It doesn’t belong on a cut.

Three: A commercial tourniquet is now on the Red Cross minimum kit list

For decades, tourniquets occupied an awkward space in first aid training — associated with military and trauma medicine, not household preparedness. That positioning has shifted. The 2024 guidelines add a manufactured tourniquet to the minimum contents for a standard first aid kit.

The key word is manufactured. Improvised tourniquets — belts, rope, shoelaces — are inconsistently effective and can cause additional injury. A commercial tourniquet (CAT, SOFT-T Wide, or similar) is designed specifically for the purpose and applies the right pressure reliably.

For life-threatening extremity bleeding, the protocol is: call 911, then apply the tourniquet two to three inches above the wound, tighten until bleeding stops, note the time. Don’t remove it. The emergency services take it from there.

Four: Naloxone — it’s over the counter now, and it’s not on the kit list

In 2023, naloxone (Narcan) became available over the counter in the United States. The 2024 first aid guidelines don’t add it to the minimum kit contents — but they acknowledge it exists, and the decision of whether to include it is a household-level judgment call.

Here’s the calculus: if your household includes someone who takes opioid medications — a post-surgical prescription, a chronic pain medication, a substance use disorder treatment — the presence of naloxone is worth thinking about. It reverses opioid overdose. It has no effect if opioids are not involved. The risk of having it in an unnecessary situation is essentially zero.

For opioid overdose: call 911 first. Then administer naloxone — nasal spray, one dose, wait two to three minutes. If no response, a second dose. The emergency services take it from there.

If you’re looking at this as a household decision: the argument for including naloxone is not that your family member will overdose. It’s that neighbors, guests, or strangers in a public setting might, and you’re equipped to respond in the minutes before EMS arrives.

The prescription layer

A first aid kit handles what happens to your body from the outside: cuts, burns, bleeding, sudden cardiac events. It holds nothing for the conditions your family takes medication for, and it can’t cover the acute bacterial infections that happen during the same stretch of time when your urgent care is closed and your doctor isn’t answering.

That layer is the JaseCase — common acute bacterial infections, prescribed by a licensed provider who reviews every request before writing a prescription. Not a first aid kit. Not a replacement for your doctor. The part of medical preparedness that first aid training was never designed to address.

To learn more about what the JaseCase covers, visit Jase.com

The audit

Open the box. Check the expiration dates — most sealed items have a two to five year shelf life, and a kit that was put together in 2018 and never opened has several items that need replacing.

Remove the peroxide. Check the aspirin count (you want enough for two to four tablets of 162-325mg). Confirm there’s a manufactured tourniquet if you want to meet the current Red Cross minimum. Decide about naloxone.

Fifteen minutes. Most of it taking things out and replacing what’s expired. That’s the audit


Aaron Asay, PA-C, DMSc, is a disaster medicine practitioner working with the Jase Medical Response team. This post is for informational purposes only and does not constitute medical advice. In a suspected cardiac or overdose emergency, call 911 immediately.*

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For Clinicians | Antibiotic Eye Drops for Pink Eye

For Clinicians | Antibiotic Eye Drops for Pink Eye

What the Evidence Says and What Schools Still Require

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Medically reviewed and edited by Kristen Carpenter, PA-C

But the school won’t take him back without the drops. I need them!

That sentence gets said at pharmacy counters and repeated into phone triage every week by the frantic parents of kids with pink eye. A kid woke up with one lid crusted shut, the front office called by 9:15, and now a parent is standing in front of one of us needing an Rx so their child can go back to school or daycare.

So we write the script. Yep. About 69% of the time, going by the claims data.¹

Today we’re talking about what those antibiotic eye drops actually do. Then why the visit is usually about authorization rather than infection, the one presentation where antibiotics make a difference (it isn’t drops), and the short list of findings that should change the plan no matter what the school form says. Let’s jump into what to do about those goopy eyes that look awful.

Do antibiotic eye drops change the course of pink eye?

A little, in the cases that are actually bacterial, and not nearly enough to explain how often we reach for them.

The 2023 Cochrane review pooled 21 trials and 8,805 patients with acute bacterial conjunctivitis. About 55% of the placebo group cleared on their own by day four to nine, compared with 68% on antibiotics.² That works out to a number needed to treat of 7 for clinical cure, against a number needed to harm of 32 for ocular adverse effects with the non-fluoroquinolone drops.³ By day six to ten the two groups have mostly converged.

That is the ceiling on the benefit. It only applies to the bacterial cases. The problem here is that we cannot reliably tell which ones those are. AAFP’s 2024 clinical review states that no single sign or symptom accurately differentiates viral from bacterial conjunctivitis,⁴ and that includes the two findings most of us rely on, purulent discharge and morning matting. So the drops go out to a mixed population in which we cannot cleanly identify the patients who stand to benefit.

The prescribing data shows how that plays out. Across 44,793 pediatric ambulatory encounters, topical antibiotics were dispensed within a day for 72% of office-based visits and 57% of ED visits, but only 34% of eye clinic visits.¹ You could reasonably say that is specialty selection, since eye clinics see referrals rather than the 9:15 phone call. Fair enough. Then look at the encounters where viral conjunctivitis was the documented diagnosis, where there is nothing for an antibiotic to act on: 28% of those children got drops anyway.¹

The 24-hour rule is school policy, not a clinical standard

Nothing in pediatric guidance requires a child with pink eye to be on drops before going back to school or daycare. The AAP position, carried in the Red Book and in Managing Infectious Diseases in Child Care and Schools, is that a child with conjunctivitis and no fever and no change in behavior does not need to be excluded, and that otherwise healthy, well-appearing children with red, watery eyes should not be excluded or isolated at all.⁵ 

Now let’s check out what states actually publish. A 2022 survey of all 50 state policies found:

  • 15 states have no conjunctivitis policy at all
  • 10 allow students to stay in school
  • 5 permit return 24 hours after starting antibiotics
  • 5 require a physician’s approval
  • 17 states plus DC give inconsistent recommendations, and not one state policy anywhere references the American Academy of Ophthalmology⁶

So the 24-hour rule that sends these families to us is written into state policy in five states.

Before we make the school nurse the villain, though: they are working from guidance that does not agree with itself. AAO’s own patient education page, updated August 2024, advises staying home until symptoms start to improve.⁷ AAP says don’t exclude. A district with no state guidance to point to picks the rule that sounds careful, and 24-hours-on-antibiotics is the one everybody has heard and feels better for parents who don’t want their kids to catch the goop eye from other kids in the class.

This is what gets awkward and that we weren’t really trained for. We were taught to make a clinical decision about an infection. What we are being asked for is authorization to re-enter a building, and it costs the family a visit and a copay to get it.

The drops are not buying a smoother course either. In that same pediatric cohort, ambulatory revisits within 14 days ran 3.1% among children who got antibiotics and 3.6% among those who did not, hospitalizations 0.03%, ED revisits 0.12%, with no differences between the groups.¹

Check out what your own state actually publishes before you write the Rx. In 15 of them, there is nothing to comply with.

Check the ears when you see the eye

There is one presentation where antibiotics clearly do the work, and the treatment is oral, not topical.

Conjunctivitis-otitis syndrome is a good one to remember in the back of your mind. Ear infections turn up alongside bacterial pink eye often. Published estimates run from 32% to 73%, and plenty of those kids never complain about ear pain.9 Haemophilus influenzae is the usual culprit. It was 70% of isolates in a cohort of 67 children with conjunctivitis plus a concurrent ear or sinus infection.⁸ Drops cannot reach the middle ear, so they do not fix the real problem. Close to 30% of US Haemophilus influenzae isolates resist ampicillin, and amoxicillin fails the same way, since the resistance is usually a beta-lactamase.¹⁰ Amox-clav holds up against almost all of them. So amox-clav or cefdinir here, not plain amoxicillin.

Look in the ears of every kid whose parent brings you a red, crusted eye, including the ones with no ear symptoms. If the ear is involved, you treat one infection with one oral antibiotic and the eye clears with it. That is the case where the right answer is an Rx, and it still isn’t drops.

What actually changes the plan

Short list, and none of it depends on sorting viral from bacterial (which is the point, since we cannot do that reliably anyway).

  • Contact lenses. Any lens wearer with a red eye gets seen today, not tomorrow. Contact-lens-associated keratitis is most often Pseudomonas, and it can leave permanent central corneal scarring and vision loss even when treatment is prompt and appropriate.¹¹ ¹² Empiric coverage needs a fluoroquinolone, and these patients belong with ophthalmology.
  • Moderate to severe pain, any change in vision, or photophobia. Not conjunctivitis territory anymore.¹¹
  • Sudden heavy purulent discharge in a sexually active adolescent or adult. Treat as gonococcal until proven otherwise. It needs systemic ceftriaxone with empiric anti-chlamydial coverage and same-day ophthalmology, because untreated it progresses to corneal melting and perforation.¹³
  • A baby under a month old.  Different illness, and it needs a clinician today rather than drops.⁷
  • Not improving, or keeps coming back. Failure to respond and recurrent episodes both go to ophthalmology.¹¹
  • Anything you find yourself wanting a steroid for. Steroids can slow corneal healing and raise intraocular pressure, and ‘needs steroids’ is itself a referral criterion.¹¹

The contact lens question is the one to build into intake. Your MA or tech can ask it before you ever walk in the room. It is most likely to get missed on a busy afternoon.

All other treatment is a warm cloth, hand hygiene, and a few days to pass.

Where preparation actually helps here

Look again at what the parent in the opener was offered. Two options: get an Rx, or keep the kid home. Nobody handed them the third thing, which was a plain statement of what their state and their district actually require and if the drops actually help the condition. That’s similar to most access problems we write about. Care is either fully authorized or fully unavailable, with nothing sanctioned in between. Usually the missing middle is a medication that should have been on the shelf before anyone needed it. Appropriate medical preparation means having the right thing ready before you need it, and sometimes the right thing turns out to be a warm cloth, four days, and knowing you are not cutting a corner.

The bottom line

Most pink eye clears on its own. Antibiotic drops help modestly in the cases that are bacterial, and we cannot reliably tell which ones those are. The 24-hour rule that sends these families to us is school policy, not medicine, and in most states nobody wrote it down at all.

Look in the ears, and know the short list that changes the plan. The rest is a conversation, and that conversation is worth more to the family than the prescription is, even if they really want that Rx when they walk in the door to see you.


Sources

  1. Shapiro DJ, Geanacopoulos AT, Subramanian SV, et al. Antibiotic Treatment and Health Care Use in Children and Adolescents With Conjunctivitis. JAMA Ophthalmology. 2024;142(8):779-780. https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2820326
  2. Chen YY, Liu SH, Nurmatov U, et al. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database of Systematic Reviews. 2023;3:CD001211. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001211.pub4/full
  3. Sonoda K, Takeuchi Y. Antibiotics for acute bacterial conjunctivitis. American Family Physician. 2023;107(6):581A-581B. https://www.aafp.org/pubs/afp/issues/2023/0600/mbtn-acute-bacterial-conjunctivitis.html
  4. Winters S, Frazier W, Winters J. Conjunctivitis: Diagnosis and Management. American Family Physician. 2024;110(2):134-144. https://www.aafp.org/pubs/afp/issues/2024/0800/conjunctivitis.html
  5. Children’s Mercy Kansas City. Conjunctivitis Care Process Model: Recommendations for Inclusion or Exclusion from Daycare/School, citing the AAP Red Book (2015) and the 2002 AAP / American Public Health Association child care exclusion recommendations. https://www.childrensmercy.org/health-care-providers/evidence-based-practice/cpgs-cpms-and-eras-pathways/conjunctivitis-care-process-model/recommendations-for-inclusion-or-exclusion-from-daycare-school/
  6. Lee T, Kuo IC. Survey of state conjunctivitis policies for school-age students. Journal of AAPOS. 2022;26(3):115.e1-115.e5. https://pubmed.ncbi.nlm.nih.gov/35378302/
  7. Mukamal R. When Do You Need Antibiotics for Pink Eye (Conjunctivitis)? American Academy of Ophthalmology, reviewed by Rupa K. Wong, MD, August 26, 2024. https://www.aao.org/eye-health/tips-prevention/over-prescription-antibiotics-pink-eye
  8. Hu YL, Lee PI, Hsueh PR, et al. Predominant role of Haemophilus influenzae in the association of conjunctivitis, acute otitis media and acute bacterial paranasal sinusitis in children. Scientific Reports. 2021;11. https://pmc.ncbi.nlm.nih.gov/articles/PMC7794412/
  9. Conjunctivitis and Conjunctivitis-Otitis Syndrome. Pediatric EM Morsels. https://pedemmorsels.com/conjunctivitis-and-conjunctivitis-otitis-syndrome/
  10. Potts CC, Rodriguez-Rivera LD, Retchless AC, et al. Antimicrobial Susceptibility Survey of Invasive Haemophilus influenzae in the United States in 2016. Microbiology Spectrum. 2022;10(3):e02579-21. https://pmc.ncbi.nlm.nih.gov/articles/PMC9241922/
  11. Hashmi MF, Gurnani B, Benson S. Conjunctivitis. StatPearls. Updated January 26, 2024. https://www.ncbi.nlm.nih.gov/books/NBK541034/
  12. Hatami H, Ghaffari Jolfayi A, Ebrahimi A, et al. Contact Lens Associated Bacterial Keratitis: Common Organisms, Antibiotic Therapy, and Global Resistance Trends: A Systematic Review. Frontiers in Ophthalmology. 2021;1:759271. https://www.frontiersin.org/journals/ophthalmology/articles/10.3389/fopht.2021.759271/full
  13. Dvorak SF, Lee C. Hyperacute Gonococcal Conjunctivitis. Brown Hospital Medicine. 2025;4(4). https://bhm.scholasticahq.com/article/144966-hyperacute-gonococcal-conjunctivitis

 

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Epinephrine & Inhaler Refill (Back to School)

Epinephrine & Inhaler Refill (Back to School)

The September Asthma Surge Is Real. Here’s Why You Need to Act in July.

By Cayla McGrath

This is one of the few pieces we write that has an actual deadline.

Every September, pediatric asthma hospitalizations spike. The surge accounts for 20-25% of all childhood asthma hospitalizations in a given year, peaking approximately 17 days after Labor Day. The timing is not a coincidence: school resumes, viral respiratory illnesses start circulating, allergen exposures change, and — critically — the summer months are when controller medication adherence is at its annual low. Kids who were managing fine all summer hit September with poorly controlled airways and a new set of triggers.

If your child has asthma or uses epinephrine, the time to act is now. Not the week before school starts. Now.

Two separate problems

The back-to-school prep for a child with asthma or a history of anaphylaxis involves two distinct tasks that families often run together: documentation and supply. They have different timelines, different contacts, and different failure modes.

Documentation

For asthma: a written Asthma Action Plan, completed and signed by your child’s provider. This is what the school nurse needs to manage your child’s asthma and know when to escalate. Without it, most schools can’t administer the rescue inhaler during the school day.

For anaphylaxis: a Food Allergy & Anaphylaxis Action Plan (or equivalent) and, in most states, a Self-Carry Authorization Form — a physician-signed document that allows your child to carry their own epinephrine auto-injector at school. The specific form varies by state. Some districts require it to go through Section 504 — a formal disability accommodation process — which has its own timeline. Check your district’s requirements now, not in August.

Section 504 is worth understanding briefly: it’s a federal civil rights protection that entitles students with disabilities (including well-controlled asthma and allergies) to reasonable accommodations at school, including the right to carry and self-administer medications. If your child doesn’t have a 504 plan and needs one to manage their condition at school, the process takes time. This is not a form to submit the week before school starts.

Supply

Two issues to address separately:

Epinephrine auto-injectors: Request two. Between 10 and 36 percent of anaphylactic reactions require a second dose of epinephrine because the first dose doesn’t fully resolve the reaction. Standard guidance from allergists and emergency medicine providers is to have two doses available. That means two auto-injectors prescribed and filled — one to stay at school, one with the child or in the family’s go bag.

Albuterol: There is an ongoing shortage of albuterol metered-dose inhalers (MDIs). If you’re having trouble getting a refill, ask your provider or pharmacist about albuterol inhalation solution — the liquid form used with a nebulizer. This is a different formulation than the MDI, but it’s the same medication. The nebulizer route requires the equipment (compressor machine, tubing, and mask or mouthpiece), which some families already have and some don’t. If this is a new option for your household, start early: getting the equipment, learning the setup, and making sure your child is comfortable with it takes more than a few days.

Heat and storage

Epinephrine degrades with heat. A car on a summer day can reach 130°F or higher — temperatures that significantly accelerate epinephrine breakdown. Don’t leave auto-injectors in a car. Keep them at room temperature, ideally below 86°F.

If your child leaves an auto-injector in a backpack during a hot outdoor activity or a car ride, it’s worth knowing: the medication may not perform as expected if it’s been heat-exposed repeatedly. Inspect the viewing window — epinephrine should be clear and colorless. Any discoloration or cloudiness is a reason to replace it.

Recently expired epinephrine: replace it, but understand the nuance

if it’s expired, replace it. Don’t use “it still probably works” as a reason to put off a refill. The whole point of back-to-school prep is to have reliable, non-expired medication in hand before your child needs it.

Undesignated school stock

Approximately two dozen states have laws allowing schools to stock undesignated epinephrine — meaning the school has auto-injectors on hand for students who don’t have their own or whose auto-injector isn’t accessible in an emergency. The specific form varies by state: some stock traditional auto-injectors, some stock nasal epinephrine (Neffy), which requires no injection.

Know your state’s law. Know whether your school has undesignated stock. This doesn’t replace your child having their own auto-injector at school — but it’s relevant information for understanding what backup exists.

The timeline

Start the documentation now: Asthma Action Plan, Food Allergy Action Plan, Self-Carry form, Section 504 if needed. These require provider sign-off and, for 504, a school meeting. July timelines leave room for delays.

Fill the prescriptions now: two auto-injectors, albuterol (and nebulizer solution if MDI is unavailable). If anything needs a prior authorization, insurance appeal, or alternative formulation conversation, better to have that happen in July than the week before school.

The September surge happens every year on the same timeline. The families who make it through without a hospitalization are usually not the ones with better-controlled asthma at baseline — they’re the ones who did this prep in July.

JaseCase is built around the everyday bacterial infections that happen year-round. It doesn’t include epinephrine or asthma controllers — those are medical devices and controller medications that require individual provider relationships and specific management plans. The principle is the same, though: knowing what you have, knowing what it covers, and taking action before you’re in the scenario.

To learn more about what the JaseCase covers, visit Jase.com


Cayla McGrath is a content strategist with Jase Medical. This post is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before using any prescription medication.

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For Clinicians | The September Asthma Epidemic

For Clinicians | The September Asthma Epidemic

Why the Controller Refill Matters More Than the Rescue Inhaler

By Dr. Jamie Wilkey, PharmD — Director of Clinical Strategy, Jase
Medically reviewed and edited by Kristen Carpenter, PA-C

Right now your patients are buying pencils, brand new white sneakers that’ll stay white for only a few days, a graphing calculator they’ll use twice, and a backpack with so much storage space. They’re paying registration fees and signing a stack of forms about photo permissions and field trips. Very few of them are making a back-to-school doctor’s appointment, and almost none of them are thinking about the inhaler that has been sitting in a drawer since late May.

Asthma doesn’t make the back-to-school list. For most of these kids, the next time they cross our radar is the third week of September, when a refill request hits the pharmacy, a parent calls the office at 7am, or the exacerbation lands in the ED.

This season is the most predictable respiratory event of the school year, and the medication that blunts it has to be restarted before the first bell. Not after the first bad night strikes.

So this is the time to dust off the inhalers. Today we’re talking about the September asthma epidemic: why hospitalizations spike two to three weeks after school starts, why the controller is the inhaler that matters here and the rescue inhaler isn’t, and what has to be signed before the surge instead of during it.

Why does childhood asthma get worse in September?

Because three separate things arrive in the same two weeks. A rhinovirus moves through a building full of kids who haven’t shared air since May. Ragweed peaks in September and mold counts climb as leaves come down. And controller inhaler use is sitting at its annual low.1,2

The size of it is bigger than you’re probably mentally calculating it is as well. In Canadian surveillance, 20% to 25% of all childhood asthma exacerbations requiring hospitalization occurred in September.¹ In school-age children the peak lands on average 17.7 days after Labor Day. Preschoolers peak at 19.4 days, and adults at 24.¹ The surge starts in the classroom and affects everyone else in the family in a domino effect after that.

You’re reading this thinking it’s just fall, and asthma is worse in fall. That was the assumption for years. Yet, it’s the school calendar that actually broke it. Scotland and Sweden send kids back in the third week of August, and that is when their peaks land. England and Canada go back the first week of September, and theirs land then.¹ Large peaks show up two to three weeks after school return in all four countries, with Scotland’s and Sweden’s smaller in amplitude.¹ Move the return date, move the peak. The epidemic has been documented in the US, the UK, Mexico, Israel, Finland, Trinidad, and Canada.1

Viral infection, mostly rhinovirus, is associated with roughly 80% of asthma exacerbations in this age group.¹ Which matters, because the medication that lowers exacerbation risk in that setting is the most important one. Prescription data show fewer asthma medication fills over the summer months, especially for children, and inhaled corticosteroid adherence is poor at baseline and likely worse in summer.¹

Controller or rescue inhaler: which one prevents the September spike?

The controller. The rescue inhaler treats an attack that has already started. The controller is what makes that attack less likely when a rhinovirus comes through the classroom. Nearly every back-to-school checklist tells parents to make sure there’s a rescue inhaler at school. That advice is correct. Yet, it’s still the wrong thing to lead with, because a rescue inhaler is what you reach for after prevention has already failed.

Current GINA guidance is pretty blunt: a short-acting beta agonist should not be used alone at any step.³ For adults and adolescents the preferred track is as-needed ICS-formoterol, which cuts severe exacerbations by roughly 60% compared with a SABA-only reliever.³ For children 6 to 11 with mild persistent asthma it’s daily low-dose ICS with as-needed SABA, and at the mildest step, ICS whenever the SABA is taken.³ So a child whose only asthma medication is albuterol is undertreated by current guidance. A child who has a controller prescription and stopped filling it in May is in the same position.

A lapsed controller medication doesn’t announce itself, either. The kid feels fine in July, which is partly what a working controller is for, and can feel superfluous so it gets dropped. There’s no symptom to report, no visit to schedule, and nothing in the chart to look at. Asthma that has been well controlled all summer can look and feel identical to asthma nobody has treated since May.

One place that this is visible is through a pharmacist’s eyes checking out their Rx fill history. A last 30-day ICS fill in April with three refills untouched is a big flag that asthma for this child is likely uncontrolled. The pharmacy for most of these families is the only place a clinician touches them before September. An albuterol refill request in August is worth two minutes of fill-history review, and a technician can pull it before the counseling conversation ever reaches you.

What has to be signed before the first bell

Almost no parents are scheduling back-to-school visits for their kids with you. So all the work is done with parent phone calls or pharmacy requests.

Three documents to know about to be able to refer patients to:

  1. The self-carry authorization. All 50 states have laws letting a student carry and self-administer their own inhaler at school.⁴ The laws vary, and many districts still require written parent and prescriber permission on file, often renewed each year. Last year’s form doesn’t always carry over so double check that. 
  2. The asthma action plan. Clinician-completed, listing medications, triggers, and the step-by-step response. Schools want a current one.
  3. The medication the school keeps. Where district policy requires a supply in the health office, that’s a second labeled inhaler and a second prescription.

A national analysis of these state policies found enough gray area in how they’re written that schools misinterpret them, and children end up without immediate access to an inhaler they are legally entitled to carry.⁵ 

One more thing that stalls August refills: albuterol shortage headlines. The current shortage is nebulizer solution, not the metered-dose inhaler most of these kids carry. But it is a good reminder that drug shortages happen frequently and it is a very good idea to have the medication you need already on the shelf, instead of hoping you can get it in an emergency.

Preparation is the whole point

School inverts the way parents can help kids during a health event. A kid in a classroom, or a student three states away at college, handles the first ten minutes alone with whatever is in the backpack or the dorm room. That’s what appropriate medical preparation means in practice: the clinical decisions made ahead of time, so nobody is improvising during the emergency.

For September asthma the thing that has to be in hand in August is the controller medication, and that comes from your office and your pharmacy. Jase carries albuterol and epinephrine auto-injectors as JaseCase add-ons, which covers the emergency layer rather than the daily one. That complements what you’re already doing. We’re here for the times you aren’t reachable.

The bottom line

The September asthma peak is already on the calendar for 2026 in your area. It’ll hit two to three weeks after the first school bell rings. The medication that changes the outcome is the controller nobody has filled (or thought of) since spring. That gets fixed in August by you, over the phone or at the counter. A fill-history check and a signed form now are cheaper than an ED visit in six weeks.


Sources

  1. Sears MR, Johnston NW. Understanding the September asthma epidemic. J Allergy Clin Immunol. 2007;120(3):526-529. The 20% to 25% September share is Canadian surveillance data.
  2. Asthma and Allergy Foundation of America. The September asthma epidemic. community.aafa.org/blog/september-asthma-epidemic
  3. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2025 update. ginasthma.org
  4. Allergy & Asthma Network. State laws on student self-carry and self-administration. advocacy.allergyasthmanetwork.org/state-laws
  5. National Analysis of State Health Policies on Students’ Right to Self-Carry and Self-Administer Asthma Inhalers at School. Journal of School Health. 2018.

 

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